cladodionen

Also Known As:

2,4-Pyrrolidinedione, 3-(5,6-dihydro-6-methyl-2H-pyran-2-ylidene)-5-(1-methylethylidene)-, (3Z)-; 3-(2-methyl-2,3-dihydropyran-6-ylidene)-5-propan-2-ylidenepyrrolidine-2,4-dione

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - cladodionen: 2
  - Pyrans: 130
    - cladodionen: 2

Experts

1.	El-Kashef, Dina H: 1 article (04/2020)
2.	Feldbrügge, Michael: 1 article (04/2020)
3.	Kalscheuer, Rainer: 1 article (04/2020)
4.	Kurtán, Tibor: 1 article (04/2020)
5.	Lee, Jungho: 1 article (04/2020)
6.	Liu, Zhen: 1 article (04/2020)
7.	Mándi, Attila: 1 article (04/2020)
8.	Müller, Werner E G: 1 article (04/2020)
9.	Pan, Feng: 1 article (04/2020)
10.	Proksch, Peter: 1 article (04/2020)

Related Diseases

1.	Neoplasms (Cancer) 02/22/2018 - "Cladodionen (1) showed cytotoxic activities against MCF-7, HeLa, HCT-116, and HL-60 human cancer cell lines with IC50 values of 18.7, 19.1, 17.9, and 9.1 µM."
2.	Lymphoma (Lymphomas) 04/01/2020 - "Cladodionen (4) exhibited cytotoxicity against the mouse lymphoma cell line L5178Y with an IC50 value of 3.7 μM, and also exhibited antifungal activity against Ustilago maydis and Saccharomyces cerevisiae, while cladosin L (1) displayed week antibacterial activity against Staphylococcus aureus ATCC 29213 and S. aureus ATCC 700699 with MIC values of 50 and 25 μM, respectively."