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mitocurcumin

compound synthesized by triphenyl-phosphonium conjugation with curcumin

Also Known As:

MitoC

Networked: 7 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Diarylheptanoids: 471
        Curcumin: 10678
        mitocurcumin: 7
      - Benzene Derivatives: 17
        Phenols: 677
        Catechols: 121
        Curcumin: 10678
        mitocurcumin: 7
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Heptanes: 70
        Diarylheptanoids: 471
        Curcumin: 10678
        mitocurcumin: 7

Experts

1.	Kutala, Vijay K: 3 articles (05/2022 - 11/2019)
2.	Sandur, Santosh K: 3 articles (05/2022 - 11/2019)
3.	Jayakumar, Sundarraj: 3 articles (01/2020 - 12/2017)
4.	Pal, Debojyoti: 2 articles (05/2022 - 12/2017)
5.	Bihani, Subhash C: 2 articles (01/2020 - 11/2019)
6.	Gupta, Gagan D: 2 articles (01/2020 - 11/2019)
7.	Kumar, Vinay: 2 articles (01/2020 - 11/2019)
8.	Kumari, Shweta: 2 articles (01/2020 - 11/2019)
9.	Sharma, Deepak: 2 articles (11/2019 - 12/2017)
10.	Checker, Rahul: 1 article (05/2022)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2017 - "The anti-cancer activity of mitocurcumin measured in terms of apoptotic cell death and the decrease in cancer stem cell frequency was accentuated by TrxR2 overexpression. " 12/01/2017 - "Here we describe the anti-tumor efficacy of mitocurcumin in lung cancer cells and its mechanism of action. " 12/01/2017 - "This study also demonstrates the role of TrxR2 and mitochondrial DNA damage in mitocurcumin mediated killing of cancer cells."
2.	Adenocarcinoma 03/01/1998 - "This study indicates that the addition of cisplatin and epirubicin to MITOC results in a significant improvement in the response rate, time to treatment failure and survival in patients with adenocarcinoma of unknown primary site."
3.	Lung Neoplasms (Lung Cancer) 12/01/2017 - "Treatment of lung cancer cells with mitocurcumin significantly decreased the frequency of cancer stem cells. " 12/01/2017 - "Here we describe the anti-tumor efficacy of mitocurcumin in lung cancer cells and its mechanism of action. " 12/01/2017 - "Mitocurcumin, showed 25-50 fold higher efficacy in killing lung cancer cells as compared to curcumin as demonstrated by clonogenic assay, flow cytometry and high throughput screening assay. "
4.	COVID-19 04/01/2023 - "To circumvent this limitation, we have used mitocurcumin (MC), a triphenyl phosphonium conjugated curcumin derivative, to study the ability to inhibit SARS-CoV-2 infection using molecular docking and molecular dynamics (MD) simulation. "
5.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2022 - "Clinical, metabolic, neuroimaging, onset, and survival data were collected from the medical records of 209 patients referred to the Beijing Children's Hospital with symmetrical basal ganglia and/or brainstem neuroimaging changes indicative of LS by 30 centers from the Chinese network of mitochondrial disease (mitoC-NET) between January 2013 and July 2021 for exploratory analysis. "

Related Drugs and Biologics

1.	Epirubicin (Ellence)
2.	Cisplatin (Platino)
3.	Curcumin
4.	Mitochondrial DNA (mtDNA)
5.	Diarylheptanoids
6.	Coloring Agents (Dyes)
7.	Cobalt

Related Therapies and Procedures

1.	Time-to-Treatment
2.	Oral Administration