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goat lung surfactant extract

Also Known As:

GLSE

Networked: 5 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Biological Products
  - goat lung surfactant extract: 5

Experts

1.	Agarwal, Ramesh: 3 articles (01/2019 - 01/2019)
2.	Jain, Kajal: 3 articles (01/2019 - 01/2019)
3.	Plakkal, Nishad: 3 articles (01/2019 - 01/2019)
4.	Sivanandan, Sindhu: 3 articles (01/2019 - 01/2019)
5.	Bahl, Monika: 2 articles (01/2019 - 01/2019)
6.	Ballambattu, Vishnu Bhat: 2 articles (01/2019 - 01/2019)
7.	Deorari, Ashok: 2 articles (01/2019 - 01/2019)
8.	Gupta, Yogendra Kumar: 2 articles (01/2019 - 01/2019)
9.	Jain, Ashish: 2 articles (01/2019 - 01/2019)
10.	Kumar, Praveen: 2 articles (01/2019 - 01/2019)

Related Diseases

1.	Newborn Respiratory Distress Syndrome 01/01/2019 - "To investigate the safety and efficacy of goat lung surfactant extract (GLSE) compared with bovine surfactant extract (beractant; Survanta®, AbbVie, USA) for the treatment of neonatal respiratory distress syndrome (RDS). "
2.	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/01/2019 - "We recently participated in a combined phase-2 and phase-3 trial investigating a new indigenous goat lung surfactant extract (GLSE) for the treatment of respiratory distress syndrome (RDS) in preterm neonates. "
3.	Infections 01/01/2019 - "Three prospective hospital-based datasets: the National Neonatal Perinatal Database (NNPD) of India, the Delhi Neonatal Infection Study (DeNIS) cohort, and the Goat Lung Surfactant Extract (GLSE)-Plus cohort were analyzed to study the causes of death among preterm neonates of less than 33 weeks' gestation admitted to the participating tertiary care hospitals in India. "
4.	Sepsis (Septicemia) 01/01/2019 - "Prematurity-related complications and sepsis contributed to 53.5% and 19.8% of deaths in the NNPD cohort, 51.0% and 25.0% in the DeNIS cohort, and 39.7% and 40.9% in GLSE-Plus cohort, respectively. "
5.	Wounds and Injuries (Trauma) 06/16/2018 - "GLSE was found to: (i) dose-dependently suppress UW-BCC1 and A431 cell growth, motility, wound closure, and clonogenicity; (ii) induce G₀/G₁ cell cycle arrest by downregulating cyclin/cdk factors while upregulating cdk inhibitors, and (iii) induce apoptosis as evidenced by cleavage of caspases-3, -8 and PARP. "

Related Drugs and Biologics

1.	goat lung surfactant extract
2.	Surface-Active Agents (Surfactants)
3.	beractant (Survanta)
4.	Cyclins
5.	Gelatin
6.	Endotoxins