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EPDMNQ

induces ROS-mediated apoptosis in liver cancer cells

Also Known As:

2,3-dihydro-2,3-epoxy-2-propylsulfonyl-5,8-dimethoxy-1,4-naphthoquinone

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthoquinones: 418
        EPDMNQ: 2
- Quinones: 434
  - Naphthoquinones: 418
    - EPDMNQ: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthoquinones: 418
      - EPDMNQ: 2

Experts

1.	Jin, Cheng-Hao: 2 articles (03/2019 - 01/2019)
2.	Li, Jin-Qian: 2 articles (03/2019 - 01/2019)
3.	Luo, Ying-Hua: 2 articles (03/2019 - 01/2019)
4.	Piao, Xian-Ji: 2 articles (03/2019 - 01/2019)
5.	Shen, Gui-Nan: 2 articles (03/2019 - 01/2019)
6.	Wang, Jia-Ru: 2 articles (03/2019 - 01/2019)
7.	Xu, Wan-Ting: 2 articles (03/2019 - 01/2019)
8.	Zhang, Tong: 2 articles (03/2019 - 01/2019)
9.	Zhang, Yi: 2 articles (03/2019 - 01/2019)
10.	Zhang, Yu: 2 articles (03/2019 - 01/2019)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 01/01/2019 - "EPDMNQ and ENDMNQ significantly inhibited the viabilities of three lung cancer cell lines and induced A549 cell cycle arrest at the G1 phase. "
2.	Liver Neoplasms (Liver Cancer) 03/01/2019 - "The results demonstrated that EPDMNQ and ENDMNQ inhibited the proliferation of liver cancer Hep3B, HepG2, and Huh7 cell lines but not that of normal liver L‑02, normal lung IMR‑90 and stomach GES‑1 cell lines. " 03/01/2019 - "The effects of EPDMNQ and ENDMNQ on cell viability, apoptosis and accumulation of reactive oxygen species (ROS) in liver cancer cells were determined by MTT cell viability assay and flow cytometry. "

Related Drugs and Biologics

1.	ENDMNQ
2.	Reactive Oxygen Species (Oxygen Radicals)