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phoenixin-20

peptide hormone cleaved from the C-terminus of protein C4orf52; ligand for GPR173

Also Known As:

phoenixin protein, rat; phoenixin-20 amide

Networked: 5 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - phoenixin-20: 5
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptide Hormones: 1347
    - phoenixin-20: 5

Experts

1.	Akdu, Sadinaz: 1 article (01/2022)
2.	Can, Ummugulsum: 1 article (01/2022)
3.	Liang, Ruobing: 1 article (01/2022)
4.	Liu, Hongmei: 1 article (01/2022)
5.	Polat, Esra: 1 article (01/2022)
6.	Wang, Su: 1 article (01/2022)
7.	Chi, Xiaoling: 1 article (12/2021)
8.	Huang, Minhong: 1 article (12/2021)
9.	Li, Zhoulan: 1 article (12/2021)
10.	Xie, Xiaohong: 1 article (12/2021)

Related Diseases

1.	Brain Infarction 01/01/2022 - "Phoenixin-20 ameliorates brain infarction by promoting microglia M2 polarization in an ischemic stroke model." 01/01/2022 - "In this study, we found that administration of Phoenixin-20 in ischemic stroke middle cerebral artery occlusion (MCAO) mice significantly reduced the brain infarction area but improved the neurological deficit score. "
2.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/01/2022 - "In this study, we found that administration of Phoenixin-20 in ischemic stroke middle cerebral artery occlusion (MCAO) mice significantly reduced the brain infarction area but improved the neurological deficit score. "
3.	Ischemic Stroke 01/01/2022 - "Phoenixin-20 ameliorates brain infarction by promoting microglia M2 polarization in an ischemic stroke model." 01/01/2022 - "In this study, we found that administration of Phoenixin-20 in ischemic stroke middle cerebral artery occlusion (MCAO) mice significantly reduced the brain infarction area but improved the neurological deficit score. "
4.	Gestational Diabetes (Gestational Diabetes Mellitus) 12/01/2021 - "Phoenixin-20 ameliorates gestational diabetes mellitus (GDM) symptoms and placental insults in an experimental mouse model."
5.	Atherosclerosis 01/01/2021 - "Furthermore, we show that agonism of GPR173 by Phoenixin-20 prevents the attachment of monocytes THP-1 to endothelial cells, which is an important therapeutic approach to preventing atherogenesis. " 01/01/2021 - "In conclusion, our study demonstrates that GPR173 agonism by Phoenixin-20 plays a protective role against ox-LDL-induced endothelial dysfunction, implying that Phoenixin-20 may have therapeutic implications in atherosclerosis." 01/01/2021 - "Phoenixin-20 Prevents ox-LDL-Induced Attachment of Monocytes to Human Aortic Endothelial Cells (HAECs): A Protective Implication in Atherosclerosis."

Related Drugs and Biologics

1.	Ligands
2.	oxidized low density lipoprotein
3.	Biomarkers (Surrogate Marker)
4.	Lipopolysaccharides

Related Therapies and Procedures

1.	Therapeutics