pongapin

furanoflavonoid from Indian medicinal plant, Pongamia pinnata (L.) Pierre

Also Known As:

2-(1,3-benzodioxol-5-yl)-3-methoxy-4H-furo(2,3-h)chromen-4-one; 4H-furo(2,3-h)-1-benzopyran-4-one, 2-(1,3-benzodioxol-5-yl)-3-methoxy-

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        pongapin: 4
      - pongapin: 4
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        pongapin: 4
      - pongapin: 4

Experts

1.	Mandal, Suvra: 2 articles (10/2021 - 04/2019)
2.	Panda, Chinmay Kumar: 2 articles (10/2021 - 04/2019)
3.	Roy, Rituparna: 2 articles (10/2021 - 04/2019)
4.	Saha, Prosenjit: 2 articles (10/2021 - 04/2019)
5.	Chakrabarti, Jayanta: 1 article (10/2021)
6.	Pal, Debolina: 1 article (04/2019)
7.	Sur, Subhayan: 1 article (04/2019)
8.	Bharate, Sandip B: 1 article (12/2018)
9.	Chaudhuri, Bhabatosh: 1 article (12/2018)
10.	Gatchie, Linda: 1 article (12/2018)

Related Diseases

1.	Psoriasis (Pustulosis Palmaris et Plantaris) 08/01/2018 - "In the present study, Karanjin and Pongapin, two important furanoflavone, constituents of Pongamia pinnata were studied in the management of Psoriasis. " 08/01/2018 - "Furthermore, Molecular docking studies were performed using CLC drug discovery workbench software version 3.0 of the studied flavones (Karanjin and Pongapin) with the receptors responsible for psoriasis (viz. " 08/01/2018 - "Overall, our results indicate that flavones (Karanjin and Pongapin) could be a natural and better alternative in curing psoriasis without any side effects." 08/01/2018 - "Docking scores of Karanjin and Pongapin with different studied receptors were found to be comparable to that of Methotrexate, a known drug for treating Psoriasis. " 08/01/2018 - "Role of nitric oxide-scavenging activity of Karanjin and Pongapin in the treatment of Psoriasis."
2.	Neoplasms (Cancer) 12/15/2018 - "The results strongly indicate the potential of methanolic seed-extract and pongapin/lanceolatin B for further development as cancer chemopreventive agents." 10/01/2021 - "The natural polyphenols Plumbagin, Pongapin and Karanjin showed anti-cancer activities in different tumors including cervical carcinoma. "
3.	Uterine Cervical Neoplasms (Cancer of the Cervix) 04/01/2019 - "Pongapin and Karanjin, furanoflavanoids of Pongamia pinnata, induce G2/M arrest and apoptosis in cervical cancer cells by differential reactive oxygen species modulation, DNA damage, and nuclear factor kappa-light-chain-enhancer of activated B cell signaling." 10/01/2021 - "Downregulation of Hyaluronic acid-CD44 signaling pathway in cervical cancer cell by natural polyphenols Plumbagin, Pongapin and Karanjin."
4.	Carcinoma (Carcinomatosis) 10/01/2021 - "The natural polyphenols Plumbagin, Pongapin and Karanjin showed anti-cancer activities in different tumors including cervical carcinoma. "
5.	Breast Neoplasms (Breast Cancer) 12/15/2018 - "Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells."

Related Drugs and Biologics

1.	karanjin
2.	Flavones
3.	Polyphenols
4.	Reactive Oxygen Species (Oxygen Radicals)
5.	Nitric Oxide (Nitrogen Monoxide)
6.	Methotrexate (Mexate)
7.	plumbagin
8.	lanceolatin B