4'-(methylamino)avarone

derivative of avarone

Also Known As:

2,5-Cyclohexadiene-1,4-dione, 2-(methylamino)-5-(((1R)-1,2,3,4,4a,7,8,8a-octahydro-1,2,4a,5-tetramethyl-1-naphthalenyl)methyl)-; 2-(Methylamino)-5-(((1R)-1,2,4a,5-tetramethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthalenyl)methyl)-1,4-benzoquinone

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - 4'-(methylamino)avarone: 2
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclohexanes: 3
        Cyclohexenes: 4
        4'-(methylamino)avarone: 2

Experts

1.	Novaković, Irena: 2 articles (03/2019 - 03/2010)
2.	Kolarević, Stoimir: 1 article (03/2019)
3.	Kostić, Jovana: 1 article (03/2019)
4.	Kračun-Kolarević, Margareta: 1 article (03/2019)
5.	Martinović, Rajko: 1 article (03/2019)
6.	Milovanović, Dragana: 1 article (03/2019)
7.	Sladić, Dušan: 1 article (03/2019)
8.	Sunjog, Karolina: 1 article (03/2019)
9.	Vuković-Gačić, Branka: 1 article (03/2019)
10.	Đorđević, Jelena: 1 article (03/2019)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2019 - "In this study, mutagenic and genotoxic potential of anti-tumor compounds avarol, avarone, and its derivatives 3'-methoxyavarone, 4'-(methylamino)avarone and 3'-(methylamino)avarone was evaluated and compared to cytostatics commonly used in chemotherapy (5-fluorouracil, etoposid, and cisplatin). "
2.	Melanoma (Melanoma, Malignant) 03/01/2010 - "The most active compound was 4'-(methylamino)avarone, with IC(50) value of 2.4 microM to melanoma Fem-X cells, and no cytotoxicity to normal lymphocytes."

Related Drugs and Biologics

1.	Cytostatic Agents
2.	Fluorouracil (Carac)
3.	Cisplatin (Platino)
4.	avarone
5.	avarol

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)