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Combretin A

A triterpene cycloartane-type isolated from the leaves of Combretum fragrans

Networked: 3 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Combretin A: 3

Experts

1.	Dawe, Amadou: 2 articles (01/2019 - 12/2018)
2.	Mbiantcha, Marius: 2 articles (01/2019 - 12/2018)
3.	Adeline, Fanta Yadang Sabine: 1 article (01/2020)
4.	Ahmad, Izhar: 1 article (01/2020)
5.	Amadou, Dawe: 1 article (01/2020)
6.	Arif, Mehreen: 1 article (01/2020)
7.	Dar, Hamza: 1 article (01/2020)
8.	Donatien, Atsamo Albert: 1 article (01/2020)
9.	Gilbert, Ateufack: 1 article (01/2020)
10.	Marius, Mbiantcha: 1 article (01/2020)

Related Diseases

1.	Diabetic Neuropathies (Diabetic Neuropathy) 01/01/2019 - "Combretin A (25 and 50 mg/kg) and Combretin B (25 and 50 mg/kg) caused antihypernociceptive, anxiolytic, and antidepressant-like effects in in STZ-induced diabetic neuropathy in mice. " 01/01/2019 - "Antihypernociceptive and neuroprotective effects of Combretin A and Combretin B on streptozotocin-induced diabetic neuropathy in mice." 01/01/2019 - "This study was designed to verify the antihypernociceptive, anxiolytic, and antidepressant-like effects of Combretin A and Combretin B (two triterpenes cycloartane-type isolated from the leaves of Combretum fragrans) in streptozotocin-induced diabetic neuropathy in mice. "
2.	Colitis 01/01/2020 - "This study revealed that Combretin A and Combretin B have anti-inflammatory, antioxidant, and curative properties against colitis experimentally induced by DSS in rats."
3.	Breast Neoplasms (Breast Cancer) 12/01/2018 - "Anti-nociceptive, anti-inflammatory and anticancer potential associated with inhibitory effects on ROS, TNFα and NO production in this study show that, Combretin A and Combretin B could be considered as the promising chemotherapeutic agents in breast cancer treatment and inflammatory disease."
4.	Pain (Aches) 12/01/2018 - "For acetic acid- or formalin-induced pain, as well as carrageenan-induced acute inflammation, Combretin A and Combretin B exhibited significant (p < 0.001) anti-nociceptive and anti-inflammatory activities. "
5.	Inflammation (Inflammations) 12/01/2018 - "For acetic acid- or formalin-induced pain, as well as carrageenan-induced acute inflammation, Combretin A and Combretin B exhibited significant (p < 0.001) anti-nociceptive and anti-inflammatory activities. "

Related Drugs and Biologics

1.	Combretin B
2.	Triterpenes
3.	Anti-Anxiety Agents (Anxiolytics)
4.	Streptozocin (Streptozotocin)
5.	Antioxidants
6.	Antidepressive Agents (Antidepressants)
7.	cycloartane
8.	Acetic Acid (Vinegar)
9.	Neuroprotective Agents
10.	Formaldehyde (Formol)

Related Therapies and Procedures

1.	Oral Administration