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IIIM-MCD-211

has activity against Mycobacterium tuberculosis

Also Known As:

1-((4-tert-butyl) phenyl))-4-(5-nitrofuran-2-yl) methyl piperazine

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitro Compounds: 66
  - Nitrofurans: 69
    - IIIM-MCD-211: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - Nitrofurans: 69
      - IIIM-MCD-211: 2
  - Piperazines: 26
    - IIIM-MCD-211: 2

Experts

1.	Magotra, Asmita: 2 articles (01/2018 - 08/2017)
2.	Nandi, Utpal: 2 articles (01/2018 - 08/2017)
3.	Sharma, Anjna: 2 articles (01/2018 - 08/2017)
4.	Sharma, Shweta: 2 articles (01/2018 - 08/2017)
5.	Singh, Gurdarshan: 2 articles (01/2018 - 08/2017)
6.	Singh, Parvinder Pal: 2 articles (01/2018 - 08/2017)
7.	Vishwakarma, Ram A: 2 articles (01/2018 - 08/2017)
8.	Wazir, Priya: 2 articles (01/2018 - 08/2017)
9.	Bokolia, Naveen: 1 article (01/2018)
10.	Khan, Inshad Ali: 1 article (01/2018)

Related Diseases

1.	Tuberculosis (Tuberculoses) 08/15/2017 - "In the present study, a simple, sensitive, specific and rapid liquid chromatography (LC) tandem mass spectrometry (MS/MS) method was developed and validated according to the Food and Drug Administration (FDA) guidelines for estimation of IIIM-MCD-211 (a potent oral candidate with promising action against tuberculosis) in mice plasma using carbamazepine as internal standard (IS). " 08/15/2017 - "Development and validation of a highly sensitive LC-ESI-MS/MS method for estimation of IIIM-MCD-211, a novel nitrofuranyl methyl piperazine derivative with potential activity against tuberculosis: Application to drug development."
2.	Oral Tuberculosis 01/01/2018 - "Physicochemical, pharmacokinetic, efficacy and toxicity profiling of a potential nitrofuranyl methyl piperazine derivative IIIM-MCD-211 for oral tuberculosis therapy via in-silico-in-vitro-in-vivo approach."
3.	Infections 01/01/2018 - "IIIM-MCD-211 is able to actively prevent progression of TB infection in chronic infection mice model. "
4.	Persistent Infection 01/01/2018 - "IIIM-MCD-211 is able to actively prevent progression of TB infection in chronic infection mice model. "

Related Drugs and Biologics

1.	Carbamazepine (Tegretol)
2.	Piperazine

Related Therapies and Procedures

1.	Therapeutics