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Tocovid

preparation of tocotrienols

Networked: 10 relevant articles (4 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Vitamin E: 8680
        Tocotrienols: 571
        Tocovid: 10
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Vitamin E: 8680
        Tocotrienols: 571
        Tocovid: 10

Experts

1.	Ahmad, Badariah: 5 articles (01/2022 - 09/2018)
2.	Phang, Sonia Chew Wen: 4 articles (01/2022 - 01/2019)
3.	Kadir, Khalid Abdul: 3 articles (01/2022 - 09/2018)
4.	Ng, En Yng: 3 articles (01/2022 - 01/2019)
5.	Ng, Yeek Tat: 3 articles (10/2021 - 01/2019)
6.	Chiew, Yilynn: 2 articles (01/2022 - 09/2018)
7.	Chuar, Pei Fen: 2 articles (01/2022 - 10/2021)
8.	Ho, J-Ian: 2 articles (01/2022 - 10/2021)
9.	Koay, Yan Yi: 2 articles (01/2022 - 10/2021)
10.	Abdul Kadir, Khalid: 2 articles (10/2021 - 05/2020)

Related Diseases

1.	Infarction (Infarctions) 08/01/2018 - "We observed that Tocovid pretreatment significantly improved the rotarod time, reduced infarct volume, decreased the number of 4-HNE, nitrotyrosine, and 8-OhdG positive cells, inhibited advanced glycation end products biomarkers RAGE, CMA, and CML expressions, and increased Nrf2 and MRP1 levels with GSSG/GSH ratio decrease. " 08/01/2018 - "Tocovid pretreatment greatly improved the mice neurobehaviors, reduced infarct volumes and decreased expressions of inflammatory markers such as tumor necrosis factor-α (TNF-α), monocyte chemotactic protein-1 (MCP-1) and ionized calcium binding adapter molecule-1 (Iba-1), and improved the damage of neurovascular units including matrix metallopeptidase 9, IgG and collagen IV after tMCAO. "
2.	Type 2 Diabetes Mellitus (MODY) 09/17/2018 - "This study aimed to investigate the effects of Tocovid on diabetic nephropathy in patients with type 2 diabetes. " 10/25/2021 - "Tocotrienol-Rich Vitamin E (Tocovid) Improved Nerve Conduction Velocity in Type 2 Diabetes Mellitus Patients in a Phase II Double-Blind, Randomized Controlled Clinical Trial." 10/25/2021 - "This study aimed to investigate the effects of tocotrienol-rich vitamin E (Tocovid SuprabioTM) on nerve conduction parameters and serum biomarkers among patients with type 2 diabetes mellitus (T2DM). "
3.	Memory Disorders (Memory Loss) 12/22/2022 - "Tocovid treatment strongly improved motor and memory deficits of APP23 mice by attenuating NOX2 expression, oxidative stress, neuroinflammation, neurovascular unit dysfunction, synaptic alteration, and Aβ deposition after 16 months. "
4.	Neuroinflammatory Diseases 12/22/2022 - "Tocovid treatment strongly improved motor and memory deficits of APP23 mice by attenuating NOX2 expression, oxidative stress, neuroinflammation, neurovascular unit dysfunction, synaptic alteration, and Aβ deposition after 16 months. "
5.	Stroke (Strokes) 08/01/2018 - "Neuroprotective Effects of Tocovid Pretreatment in a Mouse Stroke Model." 12/22/2022 - "Our previous studies showed that a novel vitamin E mixture, Tocovid, had potential neuroprotective effects in a stroke mice model and an AD cell model. "

Related Drugs and Biologics

1.	Tocotrienols
2.	Vitamin E
3.	Biomarkers (Surrogate Marker)
4.	Metalloproteases (Metalloproteinases)
5.	Glutathione Disulfide (GSSG)
6.	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)
7.	Advanced Glycation End Products
8.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
9.	Immunoglobulin G (IgG)
10.	Collagen

Related Therapies and Procedures

1.	Radiotherapy