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CB65

a specific cannabinoid CB2 receptor agonist

Also Known As:

CB65 compound; N-cyclohexyl-7-chloro-1-(2-(4-morpholinyl)ethyl)quinolin-4(1H)-one-3-carboxamide

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclohexanes: 3
        CB65: 3
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxazines: 9
    - Morpholines: 6
      - CB65: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - CB65: 3

Experts

1.	Babapour, Vahab: 1 article (06/2016)
2.	Baghbanzadeh, Ali: 1 article (06/2016)
3.	Keyshams, Negar: 1 article (06/2016)
4.	Zendehdel, Morteza: 1 article (06/2016)
5.	Farsandaj, Narges: 1 article (02/2013)
6.	Ghahremani, Mohammad Hossein: 1 article (02/2013)
7.	Lavasani, Nasir Jafar: 1 article (02/2013)
8.	Majdzadeh, Maryam: 1 article (02/2013)
9.	Ostad, Seyed Nasser: 1 article (02/2013)
10.	Parsa, Maliheh: 1 article (02/2013)

Related Diseases

1.	Liver Neoplasms (Liver Cancer) 02/01/2013 - "These data suggest ACEA and CB65 as an option for novel treatment of hepatocellular cancer. "
2.	Osteosarcoma (Osteogenic Sarcoma) 09/23/2023 - "CB65 and novel CB65 liposomal system suppress MG63 and Saos-2 osteosarcoma cell growth in vitro." 09/23/2023 - "In this study, we confirmed CB2 receptor expression in MG63 and Saos-2 osteosarcoma cells by qRT-PCR and flow cytometry (FCM), then reported the reduction effect of synthetic specific CB2 receptor agonist CB65 on the proliferation of osteosarcoma cells by WST-1 (water-soluble tetrazolium-1) and RTCA (real-time impedance-based proliferation). " 09/23/2023 - "The specific antiproliferative effect of CB65 on osteosarcoma cells was inhibited by CB2 antagonist AM630. " 09/23/2023 - "Our results demonstrate the CB2 receptor-mediated antiproliferative and apoptotic effect of a new liposomal CB65 delivery system on osteosarcoma cells that can be used as a targeted and intelligent tool for bone tumors to ameliorate pediatric bone cancers following in vivo validation."
3.	Neoplasms (Cancer) 09/23/2023 - "Our results demonstrate the CB2 receptor-mediated antiproliferative and apoptotic effect of a new liposomal CB65 delivery system on osteosarcoma cells that can be used as a targeted and intelligent tool for bone tumors to ameliorate pediatric bone cancers following in vivo validation."
4.	Hyperphagia (Overeating) 06/01/2016 - "Moreover, co-administration of CB65 plus CNQX significantly increased CB65- induced hyperphagia in FD3 neonatal layer-type chickens (P < 0.001). "

Related Drugs and Biologics

1.	CB2 Cannabinoid Receptor
2.	6-Cyano-7-nitroquinoxaline-2,3-dione (6 Cyano 7 nitroquinoxaline 2,3 dione)
3.	iodopravadoline (AM 630)