HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

leucyl- glycyl- threonyl- phenylalanyl- leucyl- lysyl- cysteine

ECL1i - extracellular loop 1 inverso; inhibits CCL2-mediated chemotaxis; ECL1i is the all-(D) peptide

Also Known As:

ECL1i peptide; LGTFLKC; Leu-Gly-Thr-Phe-Leu-Lys-Cys; d(LGTFLKC)

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - leucyl-glycyl-threonyl-phenylalanyl-leucyl-lysyl-cysteine: 2

Experts

1.	Brody, S L: 1 article (10/2016)
2.	Combadiere, C: 1 article (10/2016)
3.	Detering, L: 1 article (10/2016)
4.	Gelman, A E: 1 article (10/2016)
5.	Gropler, R J: 1 article (10/2016)
6.	Hsiao, H-M: 1 article (10/2016)
7.	Kreisel, D: 1 article (10/2016)
8.	Krupnick, A S: 1 article (10/2016)
9.	Li, W: 1 article (10/2016)
10.	Liu, Y: 1 article (10/2016)

Related Diseases

1.	Atherosclerosis 02/02/2023 - "A 7-D-amino acid peptidic CCR2 inhibitor called extracellular loop 1 inverso (ECL1i), d(LGTFLKC) has been identified and labeled to obtain a new probe for positron emission tomography in pulmonary fibrosis, heart injury, abdominal aortic aneurysm inflammation, atherosclerosis, head and neck cancer. "
2.	Abdominal Aortic Aneurysm 02/02/2023 - "A 7-D-amino acid peptidic CCR2 inhibitor called extracellular loop 1 inverso (ECL1i), d(LGTFLKC) has been identified and labeled to obtain a new probe for positron emission tomography in pulmonary fibrosis, heart injury, abdominal aortic aneurysm inflammation, atherosclerosis, head and neck cancer. "
3.	Reperfusion Injury 10/01/2016 - "Both 64 Cu-radiolabeled ECL1i peptide radiotracer (64 Cu-DOTA-ECL1i) and ECL1i-conjugated gold nanoclusters doped with 64 Cu (64 CuAuNCs-ECL1i) showed specific detection of CCR2, which is upregulated during ischemia-reperfusion injury after lung transplantation. "
4.	Pulmonary Fibrosis (Fibrosing Alveolitis) 02/02/2023 - "A 7-D-amino acid peptidic CCR2 inhibitor called extracellular loop 1 inverso (ECL1i), d(LGTFLKC) has been identified and labeled to obtain a new probe for positron emission tomography in pulmonary fibrosis, heart injury, abdominal aortic aneurysm inflammation, atherosclerosis, head and neck cancer. "
5.	Inflammation (Inflammations) 02/02/2023 - "A 7-D-amino acid peptidic CCR2 inhibitor called extracellular loop 1 inverso (ECL1i), d(LGTFLKC) has been identified and labeled to obtain a new probe for positron emission tomography in pulmonary fibrosis, heart injury, abdominal aortic aneurysm inflammation, atherosclerosis, head and neck cancer. "

Related Drugs and Biologics

1.	Gold
2.	Acids

Related Therapies and Procedures

1.	Lung Transplantation