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EDP-239

has antiviral activity; structure in first source

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzimidazoles: 245
      - EDP-239: 1
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Branched-Chain Amino Acids: 2289
    - Valine: 1999
      - EDP-239: 1
  - Essential Amino Acids: 1152
    - Valine: 1999
      - EDP-239: 1

Experts

1.	Brasher, Bradley B: 1 article (10/2016)
2.	Jiang, Lijuan: 1 article (10/2016)
3.	Jones, Christopher T: 1 article (10/2016)
4.	Lin, Kai: 1 article (10/2016)
5.	McAllister, Nicole: 1 article (10/2016)
6.	Or, Yat Sun: 1 article (10/2016)
7.	Owens, Christopher M: 1 article (10/2016)
8.	Polemeropoulos, Alex: 1 article (10/2016)
9.	Rhodin, Michael H J: 1 article (10/2016)
10.	Wong, Kelly A: 1 article (10/2016)

Related Diseases

1.

10/01/2016 - "EDP-239, a potent and selective hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor developed for the treatment of HCV infection, has been investigated in vitro and in vivo This study sought to characterize genotypic changes in the HCV NS5A sequence of genotype 1 (GT1) replicons and to compare those changes to GT1 viral RNA mutations isolated from clinical trial patients. "

Related Drugs and Biologics

1.	Viral RNA
2.	Proteins (Proteins, Gene)