cinnamoyloxy-mammeisin
isolated from Geopropolis; atenuates inflammatory process by inhibiting cytokine production: involving MAPK, AP-1, and NF-κB; structure in first source
Networked: 3
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Experts
| 1. | Franchin, Marcelo:
3 articles
(08/2022 - 02/2016)
|
| 2. | Ikegaki, Masaharu:
2 articles
(01/2017 - 02/2016)
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| 3. | Rosalen, Pedro Luiz:
2 articles
(01/2017 - 02/2016)
|
| 4. | da Cunha, Marcos Guilherme:
2 articles
(01/2017 - 02/2016)
|
| 5. | de Alencar, Severino Matias:
2 articles
(01/2017 - 02/2016)
|
| 6. | Alves-Filho, José C:
1 article
(08/2022)
|
| 7. | Cunha, Fernando Q:
1 article
(08/2022)
|
| 8. | Cunha, Thiago M:
1 article
(08/2022)
|
| 9. | César Paraluppi, Murilo:
1 article
(08/2022)
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| 10. | Damasceno, Luis Eduardo Alves:
1 article
(08/2022)
|
Related Diseases
| 1. | Encephalomyelitis (Myeloencephalitis)
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| 2. | Periodontitis
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| 3. | Inflammation (Inflammations)
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| 4. | Colonic Neoplasms (Colon Cancer)
02/01/2016
- " Fractionation of geopropolis from Melipona scutellaris, guided by antiproliferative activity against two colon cancer cell lines (COLO205 and KM12), led to the isolation of two new cinnamic acid esters, mammea-type coumarins 5,7-dihydroxy-6-(3-methyl-2-butenyl)-8-(4-cinnamoyl-3-methyl-1-oxobutyl)-4-propyl-coumarin (1) and 5,7-dihydroxy-6-(4-cinnamoyl-3-methyl-1-oxobutyl)-4-phenylcoumarin (2), along with five known coumarins, mammeigin (3), hydroxymammeigin (4), mammeisin (5), cinnamoyloxy-mammeisin (6), and mammein (7), and the prenylated benzophenone ent-nemorosone (8). "
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