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U-47700

street drugs

Also Known As:

3,4-dichloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide

Networked: 12 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Doerr, Adrian A: 2 articles (05/2022 - 12/2021)
2.	Laschke, Matthias W: 2 articles (05/2022 - 12/2021)
3.	Menger, Michael D: 2 articles (05/2022 - 12/2021)
4.	Meyer, Markus R: 2 articles (05/2022 - 12/2021)
5.	Nordmeier, Frederike: 2 articles (05/2022 - 12/2021)
6.	Schaefer, Nadine: 2 articles (05/2022 - 12/2021)
7.	Schmidt, Peter H: 2 articles (05/2022 - 12/2021)
8.	Walle, Nadja: 2 articles (05/2022 - 12/2021)
9.	Potente, Stefan: 1 article (05/2022)
10.	Lehr, Thorsten: 1 article (12/2021)

Related Diseases

1.	Body Weight (Weight, Body) 03/24/2023 - "For this purpose, 12 domestic pigs received an intravenous dose of 100 µg/kg body weight (BW) U-47700 or 1,000 µg/kg BW tramadol, respectively. " 05/20/2022 - "Twelve pigs received an intravenous dose of 100 µg/kg body weight (BW) U-47700 or 1,000 µg/kg BW tramadol. " 12/01/2021 - "As an alternative animal experimental approach, six pigs per drug received a single intravenous dose of 100 µg/kg body weight (BW) of U-47700 or 1000 µg/kg BW of tramadol to evaluate whether this species is suitable to assess the TK of NSOs. "
2.	Respiratory Insufficiency (Respiratory Failure) 01/01/2021 - "Several times more potent than morphine, U-47700 has high abuse potential and may cause clinical neurotoxicity, euphoria, respiratory depression and occasional mortality. " 01/01/2017 - "We report a patient who suffered respiratory failure and depressed level of consciousness after recreationally using a novel synthetic opioid labeled U-47700. "
3.	Opiate Overdose 11/03/2017 - "This report describes opioid overdose deaths during July-December 2016 that tested positive for fentanyl, fentanyl analogs, or U-47700, an illicit synthetic opioid, in 10 states participating in CDC's Enhanced State Opioid Overdose Surveillance (ESOOS) program.* Fentanyl analogs are similar in chemical structure to fentanyl but not routinely detected because specialized toxicology testing is required. " 11/01/2016 - "The mean and median blood concentrations for U-47700 were 253 ng/mL (±150) and 247 ng/mL, respectively, range 17-490 ng/mL. The mean and median blood concentrations for furanyl fentanyl were 26 ng/mL (±28) and 12.9 ng/mL, respectively, range 2.5-76 ng/mL. Given the widespread geographical distribution and increase in prevalence in postmortem casework, toxicology testing should be expanded to include testing for "designer opioids" in cases with histories consistent with opioid overdose but with no traditional opioids present or insufficient quantities to account for death."
4.	Drug-Related Side Effects and Adverse Reactions 11/01/2017 - "Multiple Drug-Toxicity Involving Novel Psychoactive Substances, 3-Fluorophenmetrazine and U-47700."
5.	Pulmonary Edema 10/01/2017 - "Patients that died after overdose with U-47700 typically presented to the hospital with pulmonary edema. "

Related Drugs and Biologics

1.	Tramadol (K315)
2.	Opioid Analgesics (Opioids)
3.	Illicit Drugs (Recreational Drugs)
4.	Morphine (MS Contin)
5.	Fentanyl (Sublimaze)
6.	Heroin (Diamorphine)
7.	N-methylbenzamide
8.	furanyl fentanyl
9.	3-fluorophenmetrazine