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TTL-315

antineoplastic

Also Known As:

2-mercaptopropionyl glycine disulfide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - TTL-315: 1

Experts

1.	DuHadaway, James: 1 article (02/2016)
2.	Prendergast, George C: 1 article (02/2016)

Related Diseases

1.	Skin Neoplasms (Skin Cancer) 02/16/2016 - "In several rodent models of aggressive breast, lung and skin cancers, TTL-315 blocked tumor growth and cooperated with the DNA damaging drug cisplatin to trigger tumor regression. "
2.	Neoplasms (Cancer) 02/16/2016 - "Our results offer preclinical proof of concept for TTL-315 as a novel antimetabolite to help selectively eradicate solid tumors by exploiting the glucose-deprived conditions of the tumor microenvironment. " 02/16/2016 - "Antimetabolite TTL-315 selectively kills glucose-deprived cancer cells and enhances responses to cytotoxic chemotherapy in preclinical models of cancer." 02/16/2016 - "In several rodent models of aggressive breast, lung and skin cancers, TTL-315 blocked tumor growth and cooperated with the DNA damaging drug cisplatin to trigger tumor regression. "

Related Drugs and Biologics

1.	Glucose (Dextrose)
2.	DNA (Deoxyribonucleic Acid)
3.	Cisplatin (Platino)
4.	Antimetabolites

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)