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ALF-5755

Recombinant human pancreatitis-associated protein (Reg3a).

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Lectins: 6782
    - C-Type Lectins: 976
      - Pancreatitis-Associated Proteins: 165
        ALF-5755: 2
  - Recombinant Proteins: 2754
    - ALF-5755: 2
Biological Factors: 2472
- Biomarkers: 240291
  - Tumor Biomarkers: 15272
    - Pancreatitis-Associated Proteins: 165
      - ALF-5755: 2
- Antigens: 143924
  - Neoplasm Antigens: 6217
    - Pancreatitis-Associated Proteins: 165
      - ALF-5755: 2

Experts

1.	Amouyal, Gilles: 1 article (01/2016)
2.	Amouyal, Paul: 1 article (01/2016)
3.	Bernuau, Jacques: 1 article (01/2016)
4.	Bréchot, Christian: 1 article (01/2016)
5.	Carbonell, Nicolas: 1 article (01/2016)
6.	Durand, François: 1 article (01/2016)
7.	Duvoux, Christophe: 1 article (01/2016)
8.	Faivre, Jamila: 1 article (01/2016)
9.	Gerken, Guido: 1 article (01/2016)
10.	Ichaï, Philippe: 1 article (01/2016)

Related Diseases

1.	Acute Liver Failure (Fulminant Hepatic Failure) 01/01/2016 - "The human C-type lectin Reg3α, referred to as ALF-5755, improved survival in an animal model of acute liver failure and was well tolerated in a phase 1 trial in humans. "
2.	Liver Diseases (Liver Disease) 01/01/2016 - "A Proof of Concept, Phase II Randomized European Trial, on the Efficacy of ALF-5755, a Novel Extracellular Matrix-Targeted Antioxidant in Patients with Acute Liver Diseases."
3.	Insulin Resistance 07/01/2022 - "We evidenced an increase in insulin sensitivity during an oral glucose tolerance test in ALF-5755 treated mice vs controls and decreased the pro-inflammatory cytokine C-X-C Motif Chemokine Ligand 5 (CXCL5). "

Related Drugs and Biologics

1.	C-Type Lectins (C-Type Lectin)
2.	Antioxidants
3.	Chemokines
4.	Cytokines
5.	Ligands
6.	Glucose (Dextrose)