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platin-B

structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organoplatinum Compounds
    - platin-B: 1

Experts

1.	Dhar, Shanta: 1 article (02/2016)
2.	Pathak, Rakesh K: 1 article (02/2016)

Related Diseases

1.

Neoplasms (Cancer)

02/24/2016 - "Enhanced activity and the ability to overcome cancer-induced resistance of Platin-B was related to adduct formation with intracellular glutathione, followed by the activity of Platin-B on the mitochondria of cells, along with its conventional nuclear activity. "
02/24/2016 - "Platin-B exhibited a superior cytotoxicity profile in cisplatin-resistant cancer cells. "
02/24/2016 - "A unique dual-acting chemotherapeutic modality, Platin-B, a prodrug of cisplatin and pipobroman-mimicking alkylating agent, was constructed to circumvent tumor resistance. "

Related Drugs and Biologics

1.	Prodrugs
2.	Pipobroman (Vercyte)
3.	Glutathione (Reduced Glutathione)
4.	Cisplatin (Platino)
5.	Alkylating Agents