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amorfrutin C

antineoplastic from the roots of Glycyrrhiza foetida; structure in first source

Also Known As:

2-hydroxy-4-methoxy-3,5-bis(3-methylbut-2-enyl)-6-phenethylbenzoic acid

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ghaedi, Kamran: 1 article (04/2018)
2.	Momenzadeh, Sara: 1 article (04/2018)
3.	Nasr Esfahani, Mohammad Hossein: 1 article (04/2018)
4.	Seyed Forootan, Farzad: 1 article (04/2018)
5.	Yousefnia, Saghar: 1 article (04/2018)
6.	Fischer, Cornelius: 1 article (01/2016)
7.	Hetterling, Gregor: 1 article (01/2016)
8.	Kliem, Magdalena: 1 article (01/2016)
9.	Micikas, Robert J: 1 article (01/2016)
10.	Plauth, Annabell: 1 article (01/2016)

Related Diseases

1.	Neoplasms (Cancer) 01/22/2016 - "Amorfrutin C exhibited striking antiproliferative effects for human colorectal cancer cells (HT-29 and T84), prostate cancer (PC-3), and breast cancer (MCF7) cells (IC50 values ranging from 8 to 16 μM in these cancer cell lines). " 04/05/2018 - "This review, specifically deals with anti-tumor and tumorigenicity effects of PPARγ and its natural and synthetic agonists including Troglitazone, Cladosporol A, B, 15-Deoxi-Δ12-14-Prostaglondin J2 (15-d-PGJ2), Ciglitazon, docosahexaenoic acid, eicosapentaenoic acid Alpha-eleostreac acid, Amorfrutin C, Sphingosine 1-phosphate, Evodiamine, Excavatolide B vs respected antagonists as GW9662, bisphenol-A-diglycidyl-ether. "
2.	Colorectal Neoplasms (Colorectal Cancer) 01/22/2016 - "Amorfrutin C exhibited striking antiproliferative effects for human colorectal cancer cells (HT-29 and T84), prostate cancer (PC-3), and breast cancer (MCF7) cells (IC50 values ranging from 8 to 16 μM in these cancer cell lines). "
3.	Prostatic Neoplasms (Prostate Cancer) 01/22/2016 - "Amorfrutin C exhibited striking antiproliferative effects for human colorectal cancer cells (HT-29 and T84), prostate cancer (PC-3), and breast cancer (MCF7) cells (IC50 values ranging from 8 to 16 μM in these cancer cell lines). "
4.	Colonic Neoplasms (Colon Cancer) 01/22/2016 - "Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria."
5.	Breast Neoplasms (Breast Cancer) 01/22/2016 - "Amorfrutin C exhibited striking antiproliferative effects for human colorectal cancer cells (HT-29 and T84), prostate cancer (PC-3), and breast cancer (MCF7) cells (IC50 values ranging from 8 to 16 μM in these cancer cell lines). "

Related Drugs and Biologics

1.	Eicosapentaenoic Acid
2.	Docosahexaenoic Acids
3.	Acids
4.	Troglitazone (Rezulin)
5.	excavatolide B
6.	2-chloro-5-nitrobenzanilide
7.	sphingosine 1-phosphate (sphingosine-1-phosphate)
8.	evodiamine
9.	2,2-bis(4-glycidyloxyphenyl)propane
10.	cladosporol A