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CSL360

a recombinant, chimeric immunoglobulin G1 (IgG1), anti-CD123 monoclonal antibody

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        CSL360: 2
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        CSL360: 2
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        CSL360: 2

Experts

1.	Bamford, Simone: 1 article (05/2015)
2.	Barnden, Megan: 1 article (05/2015)
3.	Basser, Russell: 1 article (05/2015)
4.	Boyd, Andrew W: 1 article (05/2015)
5.	Bradstock, Kenneth F: 1 article (05/2015)
6.	Busfield, Samantha: 1 article (05/2015)
7.	DeWitte, Mark: 1 article (05/2015)
8.	Durrant, Simon: 1 article (05/2015)
9.	He, Simon Z: 1 article (05/2015)
10.	Hertzberg, Mark S: 1 article (05/2015)

Related Diseases

1.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 05/01/2015 - "A Phase 1 study of the safety, pharmacokinetics and anti-leukemic activity of the anti-CD123 monoclonal antibody CSL360 in relapsed, refractory or high-risk acute myeloid leukemia."
2.	Leukemia 11/01/2014 - "CSL360 is a chimeric IgG1 monoclonal antibody that recognizes CD123 (IL-3 receptor α-subchain) expressed in the absence of CD131 (β-subchain), an epitope that is displayed by leukemia stem cells (LSCs). "

Related Drugs and Biologics

1.	Monoclonal Antibodies
2.	Immunoglobulin G (IgG)
3.	Epitopes