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physachenolide C

has antineoplastic activity; structure in first source

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Gunatilaka, A A Leslie: 4 articles (07/2022 - 01/2021)
2.	Xu, Ya-Ming: 4 articles (07/2022 - 01/2021)
3.	Liu, Manping X: 3 articles (07/2022 - 12/2021)
4.	Wijeratne, E M Kithsiri: 3 articles (07/2022 - 01/2021)
5.	Adams, Anngela C: 2 articles (07/2022 - 01/2022)
6.	Bosenberg, Marcus W: 2 articles (07/2022 - 01/2022)
7.	Castro-Ochoa, Karla F: 2 articles (07/2022 - 01/2022)
8.	Charos, Alexandra: 2 articles (07/2022 - 01/2022)
9.	Hastings, K Taraszka: 2 articles (07/2022 - 01/2022)
10.	Kang, Paul: 2 articles (07/2022 - 01/2022)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2022 - "Our prior studies support the anti-cancer activity of the 17β-hydroxywithanolide class of natural products, including physachenolide C (PCC). " 01/01/2021 - "Screening for sensitizers of cancer cells to TRAIL-mediated apoptosis identified a natural product of the 17β-hydroxywithanolide (17-BHW) class, physachenolide C (PCC), as a promising hit. " 07/01/2022 - "Corrigendum to "Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest"." 01/01/2022 - "Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest."
2.	Melanoma (Melanoma, Malignant) 07/01/2022 - "Corrigendum to "Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest"." 01/01/2022 - "Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest." 12/24/2021 - "Physachenolide C (1) is a 17β-hydroxywithanolide natural product with a unique anticancer potential, as it exhibits potent and selective in vitro antiproliferative activity against prostate cancer (PC) cells and promotes TRAIL-induced apoptosis of renal carcinoma (RC) and poly I:C-induced apoptosis of melanoma cells. "
3.	Prostatic Neoplasms (Prostate Cancer) 12/24/2021 - "Physachenolide C (1) is a 17β-hydroxywithanolide natural product with a unique anticancer potential, as it exhibits potent and selective in vitro antiproliferative activity against prostate cancer (PC) cells and promotes TRAIL-induced apoptosis of renal carcinoma (RC) and poly I:C-induced apoptosis of melanoma cells. "
4.	Renal Cell Carcinoma (Grawitz Tumor) 12/24/2021 - "Physachenolide C (1) is a 17β-hydroxywithanolide natural product with a unique anticancer potential, as it exhibits potent and selective in vitro antiproliferative activity against prostate cancer (PC) cells and promotes TRAIL-induced apoptosis of renal carcinoma (RC) and poly I:C-induced apoptosis of melanoma cells. "

Related Drugs and Biologics

1.	Poly I-C