human estrogen receptor alpha 36

02/01/2010 - "To investigate the mechanisms behind this paradox, we determined the differences between the transcriptional profiles of ER-alpha36 and full-length ER-alpha (ER-alpha66) in breast cancers and matched normal tissues. "
02/01/2010 - "Quantitative profiles of the mRNAs of ER-alpha and its novel variant ER-alpha36 in breast cancers and matched normal tissues."
07/01/2010 - "Higher levels of ER-alpha36 mRNA were expressed in 17 of 22 (77.27%) tumor specimens examined compared to the paired normal tissues (p<0.05). "
02/01/2010 - "Breast cancers expressed lower ER-alpha36 mRNA levels than matched normal tissues regardless of their ER-alpha66 expression status. "
02/01/2010 - "We analyzed ER-alpha36 and ER-alpha66 messenger RNA (mRNA) levels in 74 pairs of breast cancers and matched normal tissues using a real-time quantitative polymerase chain reaction (PCR) assay, and correlated the results with their clinicopathological characteristics. "

02/01/2010 - "Down-regulation of ER-alpha36 is associated with carcinogenesis and progression of breast cancer."
01/01/2008 - "As ER-alpha36 may play important roles in breast cancer tumorigenesis, it is of clinical importance to examine the expression pattern of ER-alpha36, in addition to that of ER-alpha66, for more comprehensive molecular profiling of breast carcinomas. "
09/24/2009 - "The aim of the present study was to investigate the role of ER-alpha36 in testosterone carcinogenesis. "
09/24/2009 - "Testosterone induces ERK and Akt phosphorylation via the membrane-initiated signaling pathways mediated by ER-alpha36, suggesting a possible involvement of ER-alpha 36 in testosterone carcinogenesis."

11/01/2008 - "So ER-alpha36 and ER-alpha46 might be implicated in the development and progression of colorectal cancers."
11/01/2008 - "We found that ER-alpha66, ER-alpha46 and ER-alpha36 mRNAs were coexpressed in all colorectal cancers and their matched normal tissues. "
11/01/2008 - "Whether the recently indentified ER-alpha splicing variants, ER-alpha36 and ER-alpha46, play a role in colorectal cancer development is unknown. "
11/01/2008 - "The decreased mRNA levels of ER-alpha36 and ER-alpha46 whereas no difference of ER-alpha66 mRNA was observed in colorectal cancers compared to their matched normal tissues. "
11/01/2008 - "In this study, we quantified the mRNA copy numbers of wild type ER-alpha (ER-alpha66), ER-alpha46 and ER-alpha36 in 35 colorectal cancers and their matched normal colorectal tissues by quantitative real-time PCR assay, and correlated their mRNA levels with the clinicopathological properties of the tumors. "

01/01/2008 - "Our experiments reveal a cytoplasmic and plasma-membrane-associated expression pattern of ER-alpha36 in both ER-alpha66-positive and -negative breast cancer samples. "
01/01/2008 - "ER-alpha36 is expressed in established ER-positive and -negative breast cancer cell lines. "
01/01/2008 - "ER-alpha36, a novel variant of ER-alpha, is expressed in ER-positive and -negative human breast carcinomas."
02/02/2010 - "ER variant ER-alpha36 enhances TAM agonist activity through activation of the membrane-initiated signaling pathways in endometrial cancer, and that ER-alpha36 is involved in de novo and acquired TAM resistance in breast cancer."
02/01/2010 - "Down-regulation of ER-alpha36 is associated with carcinogenesis and progression of breast cancer."

07/01/2010 - "ER-alpha36 expression may be used as a predictive marker for lymph node metastasis of gastric cancer."
07/01/2010 - "ER-alpha36 expression is highly correlated with lymph node metastasis in human gastric cancer (P<0.05). "
07/01/2010 - "A variant of estrogen receptor-alpha, ER-alpha36 is expressed in human gastric cancer and is highly correlated with lymph node metastasis."
02/01/2010 - "Down-regulation of ER-alpha36 mRNA was correlated with local progression, lymph node metastasis, and advanced cancer stage. "
11/01/2008 - "ER-alpha36 mRNA was decreased significantly in Dukes' C+D compared to Dukes' A+B stage tumors (P=0.017), and the expression of ER-alpha36 mRNA in N(1)/N(2) was lower than that in N(0) lymph node metastasis (P=0.049). "