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dehydrodieugenol B

an immunomodulator and Antileishmanial from Nectandra leucantha; structure in first source

Also Known As:

1-(8-propenyl)-3-(1'-(8'-propenyl)-3'-methoxyphenoxy)-4-hydroxy-5-methoxybenzene

Networked: 6 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Phenyl Ethers: 8
        Anisoles
        dehydrodieugenol B: 6
- Ethers: 242
  - Methyl Ethers: 19
    - Anisoles
      - dehydrodieugenol B: 6
  - Phenyl Ethers: 8
    - Anisoles
      - dehydrodieugenol B: 6

Experts

1.	Chavan, Shrawan R: 1 article (01/2021)
2.	Dandekar, Prasad D: 1 article (01/2021)
3.	Dhavale, Dilip D: 1 article (01/2021)
4.	Kadlag, Pranita P: 1 article (01/2021)
5.	Kotmale, Amol S: 1 article (01/2021)
6.	RaviKumar, Ameeta: 1 article (01/2021)
7.	Sawant, Sangeeta V: 1 article (01/2021)
8.	Banzato, Rosana: 1 article (01/2021)
9.	Bittencourt-Mernak, Márcia I: 1 article (01/2021)
10.	Lago, João H G: 1 article (01/2021)

Related Diseases

1.	Schistosomiasis (Bilharziasis) 10/31/2023 - "The superior efficacy of dehydrodieugenol B (1) compared to praziquantel in premature infections holds the potential to advance the development of new molecular prototypes for schistosomiasis treatment."
2.	Pneumonia (Pneumonitis) 01/01/2021 - "Therefore, eugenol and dehydrodieugenol B ameliorates several features of experimental ALI and could be considered as a pharmacological tool to ameliorate acute lung inflammation." 01/01/2021 - "Effects of Eugenol and Dehydrodieugenol B from Nectandra leucantha against Lipopolysaccharide (LPS)-Induced Experimental Acute Lung Inflammation."
3.	Infections 10/31/2023 - "The superior efficacy of dehydrodieugenol B (1) compared to praziquantel in premature infections holds the potential to advance the development of new molecular prototypes for schistosomiasis treatment."
4.	Schistosomiasis mansoni 10/31/2023 - "This study examines the potential of dehydrodieugenol B (1) and its methyl ether (2), derived from the leaves of the Brazilian Nectandra leucantha plant (Lauraceae), in combatting Schistosoma mansoni infections through a preclinical approach. " 10/31/2023 - "Evaluating the Antischistosomal Activity of Dehydrodieugenol B and Its Methyl Ether Isolated from Nectandra leucantha-A Preclinical Study against Schistosoma mansoni Infection."
5.	Visceral Leishmaniasis (Kala Azar) 07/20/2023 - "This study emphasizes the potential of dehydrodieugenol B analogues as new candidates for the treatment of visceral leishmaniasis and suggests 24 to be a suitable compound for future optimization, including mechanism of action and pharmacokinetic studies." 07/20/2023 - "Biological activity and structure-activity relationship of dehydrodieugenol B analogues against visceral leishmaniasis."

Related Drugs and Biologics

1.	Praziquantel (Biltricide)
2.	Eugenol
3.	Ether (Diethyl Ether)
4.	Lipopolysaccharides
5.	Hexanes
6.	Collagen
7.	Benzene (Benzole)
8.	Amylases