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STF-31

antineoplastic

Also Known As:

4-((((4-(1,1-dimethylethyl)phenyl)sulfonyl)amino)methyl)-N-3-pyridinylbenzamide

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - STF-31: 4

Experts

1.	Beier, Imke: 1 article (10/2018)
2.	Kraus, Dominik: 1 article (10/2018)
3.	Kuerpig, Stefan: 1 article (10/2018)
4.	Meisenheimer, Michael: 1 article (10/2018)
5.	Probstmeier, Rainer: 1 article (10/2018)
6.	Reckenbeil, Jan: 1 article (10/2018)
7.	Stark, Helmut: 1 article (10/2018)
8.	Veit, Nadine: 1 article (10/2018)
9.	Winter, Jochen: 1 article (10/2018)
10.	Adams, Drew J: 1 article (10/2014)

Related Diseases

1.	Neoplasms (Cancer) 08/03/2011 - "Activity of STF-31 in these experimental renal tumors can be monitored by [(18)F]fluorodeoxyglucose uptake by micro-positron emission tomography imaging, and therefore, these agents may be readily tested clinically in human tumors. " 10/17/2014 - "We profiled the sensitivity of 679 cancer cell lines to STF-31 and found that the pattern of response is tightly correlated with sensitivity to three different inhibitors of nicotinamide phosphoribosyltransferase (NAMPT). " 02/23/2023 - "(2) Methods: the proliferation and survival rate of tumor cells was significantly affected by the GLUT-inhibitors fasentin and WZB1127, as well as by the NAMPT inhibitors GMX1778 and STF-31. " 10/01/2018 - "Here, we aimed to assess the impact of the glucose transporter (GLUT) inhibitors fasentin and WZB117, and the nicotinamide phosphoribosyltransferase (NAMPT) inhibitors GMX1778 and STF-31 on tumor cell proliferation and survival, as well as on glucose uptake. " 10/01/2018 - "Tumor-derived A172 (glioblastoma), BHY (oral squamous cell carcinoma), HeLa (cervix adenocarcinoma), HN (head neck cancer), HT-29 (colon carcinoma) and MG-63 (osteosarcoma) cells were treated with fasentin, WZB117, GMX1778 and STF-31. "
2.	Osteosarcoma (Osteogenic Sarcoma) 10/01/2018 - "Tumor-derived A172 (glioblastoma), BHY (oral squamous cell carcinoma), HeLa (cervix adenocarcinoma), HN (head neck cancer), HT-29 (colon carcinoma) and MG-63 (osteosarcoma) cells were treated with fasentin, WZB117, GMX1778 and STF-31. "
3.	Head and Neck Neoplasms (Head and Neck Cancer) 10/01/2018 - "Tumor-derived A172 (glioblastoma), BHY (oral squamous cell carcinoma), HeLa (cervix adenocarcinoma), HN (head neck cancer), HT-29 (colon carcinoma) and MG-63 (osteosarcoma) cells were treated with fasentin, WZB117, GMX1778 and STF-31. "
4.	Glioblastoma (Glioblastoma Multiforme) 10/01/2018 - "Tumor-derived A172 (glioblastoma), BHY (oral squamous cell carcinoma), HeLa (cervix adenocarcinoma), HN (head neck cancer), HT-29 (colon carcinoma) and MG-63 (osteosarcoma) cells were treated with fasentin, WZB117, GMX1778 and STF-31. "
5.	Renal Cell Carcinoma (Grawitz Tumor) 10/17/2014 - "The small-molecule probes STF-31 and its analogue compound 146 were discovered while searching for compounds that kill VHL-deficient renal cell carcinoma cell lines selectively and have been reported to act via direct inhibition of the glucose transporter GLUT1. "

Related Drugs and Biologics

1.	Nicotinamide Phosphoribosyltransferase
2.	Facilitative Glucose Transport Proteins (Glucose Transporter)
3.	fasentin
4.	N- (6- chlorophenoxyhexyl)- N''- cyano- N''- 4- pyridylguanidine (CHS 828)
5.	Glucose (Dextrose)
6.	WZB117