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3,3,3- trifluoro- 2- (4- isobutylphenyl)propanoic acid

inhibits alpha-methylacyl coenzyme A racemase; has antineoplastic activity; structure in first source

Also Known As:

trifluoroibuprofen

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylpropionates
      - Ibuprofen: 5288
        3,3,3-trifluoro-2-(4-isobutylphenyl)propanoic acid: 1

Experts

1.	Carnell, Andrew J: 1 article (01/2014)
2.	Cesare, Ernesto Di: 1 article (01/2014)
3.	Festuccia, Claudio: 1 article (01/2014)
4.	Gibson, Robert: 1 article (01/2014)
5.	Gravina, Giovanni Luca: 1 article (01/2014)
6.	Hughes, Shaun: 1 article (01/2014)
7.	Kirk, Ralph: 1 article (01/2014)
8.	Lian, Lu-Yun: 1 article (01/2014)
9.	Mancini, Andrea: 1 article (01/2014)
10.	Muzi, Paola: 1 article (01/2014)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 01/01/2014 - "Trifluoroibuprofen inhibits α-methylacyl coenzyme A racemase (AMACR/P504S), reduces cancer cell proliferation and inhibits in vivo tumor growth in aggressive prostate cancer models."
2.	Neoplasms (Cancer) 01/01/2014 - "Trifluoroibuprofen inhibits α-methylacyl coenzyme A racemase (AMACR/P504S), reduces cancer cell proliferation and inhibits in vivo tumor growth in aggressive prostate cancer models."

Related Drugs and Biologics

1.	Racemases and Epimerases (Epimerases and Racemases)
2.	Coenzyme A (CoA)