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diplacone

structure in first source

Networked: 6 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavanones: 184
        diplacone: 6
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavanones: 184
        diplacone: 6

Experts

1.	Hošek, Jan: 3 articles (05/2020 - 03/2015)
2.	Šmejkal, Karel: 2 articles (01/2017 - 03/2015)
3.	Baďo, Zuzana: 1 article (05/2020)
4.	Cox, Eric: 1 article (05/2020)
5.	Devriendt, Bert: 1 article (05/2020)
6.	Faldyna, Martin: 1 article (05/2020)
7.	Hanuš, Jaroslav: 1 article (05/2020)
8.	Kavanová, Lenka: 1 article (05/2020)
9.	Prokopec, Vadym: 1 article (05/2020)
10.	Rotrekl, Dominik: 1 article (05/2020)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2019 - "These natural compounds have attracted much attention because of their various biological activities, including antioxidation, anti-inflammation, cytotoxic activity and various enzymatic inhibitions, etc. Among them, diplacone, a major Paulownia component, was considered to have promise for applications in medicine. " 05/30/2020 - "The obtained results indicate a potentially beneficial effect of the incorporation of curcumin or diplacone into GPs against inflammation." 01/01/2017 - "Furthermore, one of the COX/LOX dual inhibitors, diplacone (14) (a major geranylated flavanone of P. tomentosa), was studied in vitro to obtain a proteomic overview of its effect on inflammation in LPS-treated THP-1 macrophages, supporting its previously observed anti-inflammatory activity and revealing the mechanism of its anti-inflammatory effect."
2.	Necrosis 01/01/2010 - "This study focused on the ability of diplacone to modulate the gene expression of pro-inflammatory tumour necrosis factor alpha and monocyte chemoattractant protein 1, and of anti-inflammatory zinc finger protein 36. " 01/01/2010 - "In this model, diplacone significantly down-regulated the expression of tumour necrosis factor alpha and monocyte chemoattractant protein 1 and up-regulated the zinc finger protein 36 expression. "
3.	Neoplasms (Cancer) 09/01/2014 - "These data suggest that diplacone analogs may protect healthy tissue surrounding tumor cells during radiotherapy to ensure better control of radiotherapy and allow higher doses of radiotherapy to be employed."
4.	Colitis 03/01/2015 - "Diplacone (1) and mimulone (2) were administered at a bolus dose of 25mg/kg by gastric gavage 48 and 24h prior to the induction of colitis by DSS and every 24h on the following days of the experiment. " 03/01/2015 - "Diplacone and mimulone ameliorate dextran sulfate sodium-induced colitis in rats."

Related Drugs and Biologics

1.	Tristetraprolin
2.	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)
3.	Dextran Sulfate
4.	Curcumin
5.	flavanone
6.	mimulone

Related Therapies and Procedures

1.	Radiotherapy