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N3-carboxymethylthymidine

structure in first source

Also Known As:

N3-CMdT

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Thymidine: 4460
        N3-carboxymethylthymidine: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Thymidine: 4460
      - N3-carboxymethylthymidine: 2
  - Deoxyribonucleosides: 34
    - Thymidine: 4460
      - N3-carboxymethylthymidine: 2

Experts

1.	Wang, Jianshuang: 2 articles (07/2017 - 02/2009)
2.	Wang, Yinsheng: 2 articles (07/2017 - 02/2009)
3.	Ji, Debin: 1 article (07/2017)
4.	Li, Lin: 1 article (07/2017)
5.	Suo, Zucai: 1 article (07/2017)
6.	Wang, Pengcheng: 1 article (07/2017)
7.	Williams, Nicole L: 1 article (07/2017)
8.	Wu, Jun: 1 article (07/2017)
9.	You, Changjun: 1 article (07/2017)
10.	Zahurancik, Walter J: 1 article (07/2017)

Related Diseases

1.	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 07/07/2017 - "Together, our study provided molecular-level insights into the impacts of the carboxymethylated DNA lesions on DNA replication in human cells, revealed the roles of individual translesion synthesis DNA polymerases in bypassing these lesions, and suggested the contributions of O6-CMdG, N3-CMdT and O4-CMdT to the mutations found in p53 gene of human gastrointestinal cancers."
2.	Neoplasms (Cancer) 02/01/2009 - "The demonstration of the formation of N3-CMdT and O(4)-CMdT in isolated DNA upon treatment with diazoacetate, together with the preparation of authentic oligodeoxyribonucleotide substrates housing these two lesions, laid the foundation for investigating the replication and repair of these lesions and for understanding their implications in the mutations observed in human gastrointestinal tumors."

Related Drugs and Biologics

1.	DNA-Directed DNA Polymerase (Polymerases, DNA)
2.	O4-carboxymethylthymidine
3.	Oligodeoxyribonucleotides
4.	DNA (Deoxyribonucleic Acid)