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INCB 3284

a CCR2 receptor antagonist

Also Known As:

INCB 3284 dimesylate; INCB3284

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	DeSantis, Anthony J: 1 article (05/2022)
2.	Enten, Garrett A: 1 article (05/2022)
3.	Gao, Xianlong: 1 article (05/2022)
4.	Majetschak, Matthias: 1 article (05/2022)
5.	Weche, McWayne: 1 article (05/2022)
6.	Alpini, Gianfranco: 1 article (07/2014)
7.	DeMorrow, Sharon: 1 article (07/2014)
8.	Frampton, Gabriel: 1 article (07/2014)
9.	Galindo, Cheryl: 1 article (07/2014)
10.	McMillin, Matthew: 1 article (07/2014)

Related Diseases

1.	Hemorrhagic Shock 01/01/2023 - "We reported previously that the CCR2 antagonist INCB3284 prevents cardiovascular collapse and reduces fluid requirements after 30min of hemorrhagic shock (HS), whereas the CCR5 antagonist Maraviroc was ineffective. " 05/01/2022 - "The Chemokine (C-C Motif) Receptor 2 Antagonist INCB3284 Reduces Fluid Requirements and Protects From Hemodynamic Decompensation During Resuscitation From Hemorrhagic Shock."
2.	Hepatic Encephalopathy 07/10/2014 - "Hepatic encephalopathy was induced in mice via injection of azoxymethane (AOM) in the presence or absence of INCB 3284 dimesylate (INCB), a chemokine receptor 2 inhibitor, or C 021 dihydrochloride (C021), a chemokine receptor 4 inhibitor. "
3.	Hemorrhage 05/01/2022 - "Third, treatment of rats with 5 μmol/kg INCB3284 or vehicle after hemorrhage and fluid resuscitation until t = 300 minutes. "

Related Drugs and Biologics

1.	CC Chemokines
2.	Chemokine Receptors
3.	Azoxymethane
4.	Maraviroc
5.	C 021 compound

Related Therapies and Procedures

1.	Resuscitation