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glyoxal- bis(4- methylthiosemicarbazonato)copper(II)

has antineoplastic activity

Also Known As:

Cu-GTSM

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Andres, Sarah A: 1 article (04/2020)
2.	Bajaj, Kritika: 1 article (04/2020)
3.	Bates, Paula J: 1 article (04/2020)
4.	Buchanan, Robert M: 1 article (04/2020)
5.	Grapperhaus, Craig A: 1 article (04/2020)
6.	Mashuta, Mark S: 1 article (04/2020)
7.	Peterson, Megan A: 1 article (04/2020)
8.	Vishnosky, Nicholas S: 1 article (04/2020)
9.	Al-Eisawi, Zaynab: 1 article (11/2015)
10.	Jansson, Patric J: 1 article (11/2015)

Related Diseases

1.

Neoplasms (Cancer)

11/01/2015 - "Fluorescence microscopy suggested that the anti-cancer activity of Cu(GTSM) was due, in part, to lysosomal membrane permeabilization (LMP). "
04/06/2020 - "In MTT assays, 4 and 6 were substantially more active against A549 cancer cells than Cu(ATSM) and were more cancer-selective (for A549 compared to IMR-90) than Cu(GTSM). "
04/01/2014 - "The copper(II) complexes of bis-thiosemicarbazones (Cu(btsc)) such as Cu(atsm) and Cu(gtsm) are neutral, lipophilic compounds that show promise as therapeutics for the treatment of certain neurological diseases and cancers. "

Related Drugs and Biologics

1.	copper (II) diacetyl- di(N(4)- methylthiosemicarbazone)
2.	Thiosemicarbazones
3.	Copper

Related Therapies and Procedures

1.	Therapeutics