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2- (3,4,5- trimethoxybenzyl)- 6- O- sulphamoyl- 7- methoxy- 1,2,3,4- tetrahydroisoquinoline

a tubulin disruptor with antineoplastic activity; structure in first source

Also Known As:

STX2484

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chander, S K: 1 article (07/2014)
2.	Day, J M: 1 article (07/2014)
3.	Ferrandis, E: 1 article (07/2014)
4.	Foster, P A: 1 article (07/2014)
5.	Jourdan, F L: 1 article (07/2014)
6.	Leese, M P: 1 article (07/2014)
7.	Newman, S P: 1 article (07/2014)
8.	Potter, B V L: 1 article (07/2014)
9.	Purohit, A: 1 article (07/2014)
10.	Reed, M J: 1 article (07/2014)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 07/15/2014 - "In breast cancer xenografts, STX2484 (20 mg kg(-1) p.o.) suppressed tumour growth by 84% after 35 days of daily dosing, with limited toxicity. " 07/15/2014 - "These studies aimed to identify STX2484's mechanism of action, in vivo efficacy and activity in taxane-resistant breast cancer models. " 07/15/2014 - "In vivo and in vitro properties of STX2484: a novel non-steroidal anti-cancer compound active in taxane-resistant breast cancer."
2.	Neoplasms (Cancer) 07/15/2014 - "In vivo and in vitro properties of STX2484: a novel non-steroidal anti-cancer compound active in taxane-resistant breast cancer."

Related Drugs and Biologics

1.	taxane