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3,15,18- trihydroxy- 18,19- secolupane- 12,19- dione 3-O-glucopyranosyl(1-2)glucopyranoside

has antineoplastic activity; isolated from Fatsia japonica; structure in first source

Also Known As:

fatsioside A

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - 3,15,18-trihydroxy-18,19-secolupane-12,19-dione 3-O-glucopyranosyl(1-2)glucopyranoside: 3

Experts

1.	Zhang, Dong-Hui: 1 article (10/2015)
2.	Zhang, Jian-You: 1 article (10/2015)
3.	Zheng, Yu-Shan: 1 article (10/2015)
4.	Cui, Xin-Guo: 1 article (05/2015)
5.	Hu, Jia: 1 article (05/2015)
6.	Liu, Jian-Hui: 1 article (05/2015)
7.	Pan, Ji-Ming: 1 article (05/2015)
8.	Shi, Hong-Zhi: 1 article (05/2015)
9.	Wang, Guang-Bin: 1 article (05/2015)
10.	Xia, Guang-Wen: 1 article (05/2015)

Related Diseases

1.	Glioma (Gliomas) 05/01/2015 - "Previous studies have shown that Fatsioside A induces growth inhibition, cell cycle arrest and apoptosis in C6 rat glioma cells and U251 human glioma cells. " 10/01/2015 - "Previous data has revealed that fatsioside A can exert growth inhibition, cell cycle arrest and induce apoptosis in human glioma cells. " 05/01/2015 - "This may provide a molecular basis for the development of Fatsioside A into a drug candidate for the treatment of malignant glioma." 05/01/2015 - "In conclusion, Fatsioside A inhibits glioma cell growth via the induction of ER stress‑mediated apoptosis. " 05/01/2015 - "Fatsioside A inhibits the growth of glioma cells via the induction of endoplasmic reticulum stress-mediated apoptosis."
2.	Necrosis 03/01/2014 - "Further investigation indicated that fatsioside A induced apoptosis and necrosis in glioma cells, and arrested the cell cycle at the G0/G1 phase."

Related Drugs and Biologics

1.	Glycosides