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glycyl-glycyl-leucine

a hypoglycemic agent that increases serum levels of both insulin and GLP-1

Also Known As:

Gly-Gly-Leu; GlyGlyLeu; diapin

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - glycyl-glycyl-leucine: 2

Experts

1.	Chen, Y Eugene: 1 article (01/2013)
2.	Ma, Zhongmin Alex: 1 article (01/2013)
3.	Pennathur, Subramaniam: 1 article (01/2013)
4.	Vivekanandan, Anuradha: 1 article (01/2013)
5.	Xue, Changyong: 1 article (01/2013)
6.	Zhang, Jifeng: 1 article (01/2013)
7.	Zhu, Tianqing: 1 article (01/2013)

Related Diseases

1.	Obesity 01/01/2013 - "Glucose tolerance tests showed that oral administration of Diapin effectively lowered blood glucose after oral glucose loading in both normal C57BL/6J mice and T2D mouse models, including KKay, db/db, ob/ob mice, and high fat diet-induced obesity/T2D mice. "
2.	Hypoglycemia (Reactive Hypoglycemia) 01/01/2013 - "In addition, Diapin treatment significantly reduced casual blood glucose in KKay diabetic mice in a time-dependent manner without causing hypoglycemia. "
3.	Fibrosis (Cirrhosis) 01/01/2023 - "Here, we report that the tripeptide DT-109 (Gly-Gly-Leu) dose-dependently attenuates steatohepatitis and fibrosis in mice. "
4.	Fatty Liver 01/01/2023 - "Here, we report that the tripeptide DT-109 (Gly-Gly-Leu) dose-dependently attenuates steatohepatitis and fibrosis in mice. "
5.	Type 2 Diabetes Mellitus (MODY) 01/01/2013 - "A tripeptide Diapin effectively lowers blood glucose levels in male type 2 diabetes mice by increasing blood levels of insulin and GLP-1."

Related Drugs and Biologics

1.	Glucagon-Like Peptide 1 (GLP 1)
2.	Insulin (Novolin)
3.	Glucose (Dextrose)
4.	Blood Glucose (Blood Sugar)

Related Therapies and Procedures

1.	Oral Administration