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glyceollin II

cholesterol-lowering soy-derived glyceollin; structure in first source

Also Known As:

(-)-glyceollin II

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Balaguer, Patrick: 1 article (02/2020)
2.	Chalmel, Frédéric: 1 article (02/2020)
3.	Efstathiou, Theo: 1 article (02/2020)
4.	Evrard, Bertrand: 1 article (02/2020)
5.	Ferriere, François: 1 article (02/2020)
6.	Lardenois, Aurélie: 1 article (02/2020)
7.	Le Guevel, Remy: 1 article (02/2020)
8.	Lecomte, Sylvain: 1 article (02/2020)
9.	Pakdel, Farzad: 1 article (02/2020)
10.	Pham, Thu Ha: 1 article (02/2020)

Related Diseases

1.	Osteoporosis 04/15/2017 - "The ability of glyceollin II to induce osteogenic differentiation in ASCs and BMSCs indicates that glyceollins hold the potential for the development of pharmacological interventions to improve clinical outcomes of patients with osteoporosis."
2.	Neoplasms (Cancer) 02/18/2020 - "To investigate the interaction between glyceollin I (GI), glyceollin II (GII) and AhR, a computational docking analysis, luciferase assays, immunofluorescence and transcriptome analyses were performed with different cancer cell lines. "
3.	Hypercholesterolemia 11/01/2023 - "Daidzin, Glycitin, Genistin, Daidzein, Glycitein, Genistein, Glyceollin I, Glyceollin II, and Glyceollin III were selected to be analyzed their interaction with 3-Hydroxy-3-Methyl-Glutaryl-Coenzyme A Reductase (HMGCR) and Sterol Regulatory Element-Binding Protein 2 (SREBP2) as key factors in cholesterol biosynthesis as well as Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) as a common target for hypercholesterolemia. "

Related Drugs and Biologics

1.	glyceollin
2.	Sterol Regulatory Element Binding Protein 2
3.	Genistein
4.	Oxidoreductases (Dehydrogenase)
5.	Luciferases
6.	Cholesterol
7.	Proprotein Convertase 9
8.	glycitin
9.	glycitein
10.	genistin