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5- (6- isopropyl- 2- methylaminopyridin- 3- yl)- (N- (1- ethyl)propyl)- 3- methoxy- 6- methylpyrazine- 2- amine

an antagonist of corticotropin releasing factor receptor 1 (CRF1 receptor); structur ein first source

Also Known As:

NGD 9002

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrazines: 150
    - 5-(6-isopropyl-2-methylaminopyridin-3-yl)-(N-(1-ethyl)propyl)-3-methoxy-6-methylpyrazine-2-amine: 1

Experts

1.	Czimmer, József: 1 article (01/2013)
2.	Hoffman, Diane C: 1 article (01/2013)
3.	Kehne, John: 1 article (01/2013)
4.	Luckey, Andrew: 1 article (01/2013)
5.	Maynard, George D: 1 article (01/2013)
6.	Million, Mulugeta: 1 article (01/2013)
7.	Taché, Yvette: 1 article (01/2013)
8.	Zhao, Jing-Fang: 1 article (01/2013)

Related Diseases

1.

Hypersensitivity (Allergy)

01/01/2013 - "We investigated the inhibitory effects of a new generation, topology 2 selective CRF1 antagonists, NGD 98-2 and NGD 9002 on exogenous and endogenous CRF-induced stimulation of colonic function and visceral hypersensitivity to colorectal distension (CRD) in conscious rats. "
01/01/2013 - "The newly developed CRF1-receptor antagonists, NGD 98-2 and NGD 9002, suppress acute stress-induced stimulation of colonic motor function and visceral hypersensitivity in rats."

Related Drugs and Biologics

1.	N- (1- ethylpropyl)- (3- methoxy- 5- (2- methoxy- 4- trifluoromethoxyphenyl)- 6- methyl- pyrazin- 2- yl)amine