Sclerosis

08/01/1990 - "The patients had severe disease; there was a high degree of glomerular sclerosis; the median serum creatinine was 137 mumol/l, the diastolic blood pressure 101 mm Hg. Reported previously was a short-term improvement in renal function, blood pressure, and renal histology. "
10/24/2023 - "The combined nomogram model scores including age, mean arterial pressure and the above five laboratory indicators indicated that mean arterial pressure and serum creatinine levels were strongly correlated with vascular sclerosis. "
09/01/2016 - "The serum creatinine level, time posttransplant, and global sclerosis frequency were insignificant among the categories. "
07/01/2013 - "Kidneys glomerular sclerosis and high creatinine levels were observed in group fed mucuna flour. "
09/01/2012 - "The number of urinary podocytes in patients with segmental sclerosis was higher than in patients without (1.05 [IQR, 0.41-1.67] per mg creatinine versus 0.28 [IQR, 0.10-0.66] per mg creatinine; P<0.01). "

11/01/1997 - "Ethanol sclerosis is a well-tolerated, safe, and effective adjunct to the management of VMs. "
11/01/2023 - "In this case, ethanol sclerosis was used to successfully manage an intrathyroidal PC. "
01/01/2022 - "Techniques included: double-balloon for distal protection to block distal flow and target the proximal portion of a large intramural vein where best signal was proximal (n=6); balloons in 2 different left ventricular summit veins for a cross-fire multivein VEA (n=4); intramural collateral vein-to-vein cannulation to reach of targeted vein via collateral with antegrade ethanol and proximal balloon block (n=2); prolonged ethanol dwell time for vein sclerosis of large intramural vein and subsequent VEA (n=3); and intramural collateral VEA (n=1). "
05/01/2020 - "Twenty-seven absolute alcohol procedures were performed for patients with intravascular sclerosis (range: 1-3, mean: 2) with one procedure required per patient (n = 2), 2 per patient (n = 5), or 3 per patient (n = 5). "
05/01/2019 - "Both LPI and RWM vibrations significantly decreased at low frequencies after infiltration of ethanol, which caused SVJ sclerosis. "

01/01/2020 - "In addition, both TLR2- and HMGB1-deficient mice showed reduced 24 hr urine protein levels and improved glomerular histological changes and sclerosis levels. "
05/21/2021 - "In this two-part proteomic study, we used two-dimensional difference gel electrophoresis (2D-DIGE) followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) to analyze EV proteins of plasma collected at diagnosis from children with nodular sclerosis HL, relapsed or not. "
12/01/1999 - "In each of the two studies the systolic blood pressure (SBP), 24 h urinary total protein, glomerular filtration rate (GFR), glomerular area, proximal tubular area and glomerular sclerosis were evaluated. "
08/01/1996 - "In conclusion, our study revealed that the major renal expression site of the human ET-2 transgene in TGR(hET-2)37 rats was within the glomeruli and caused the development of glomerulo-sclerosis with significantly increased protein excretion that is independent of blood pressure. "
01/01/1996 - "In conclusion, meta-analysis of data from studies examining urinary protein excretion revealed a significant positive correlation with glomerular sclerosis in both experimental models and human diseases. "

09/01/2002 - "Sonographically guided percutaneous injection of 1% polidocanol for sclerosis of peripheral vascular lesions is simple, effective, and safe. "
09/01/2020 - "In this paper, we report on an improved surgical technique involving lauromacrogol sclerosis directly under laparoscopic fenestration. "
05/01/2021 - "Sclerosis with foam and liquid polidocanol were superior to the other groups, but specially polidocanol foam at the expense of greater frequency of adverse events."
11/01/2004 - "[Allergic respiratory disorders and vein sclerosis with lauromacrogol 400]."
05/01/2003 - "The procedures were performed on a out-patient basis with ultrasound assistance and using 3% Polidocanol for sclerosis. "

03/06/2024 - "Pathological analysis showed that Nam improved the structure of glomerular basement membrane, ameliorated glomerular sclerosis, and decreased the accumulation of extracellular matrix and collagen. "
10/01/2008 - "Supportive histopathologic findings consisting of either fascial sclerosis or increased fibroblast cellularity with sclerotic collagen bundles in the deep reticular dermis and/or subcutaneous septa may help to confirm this diagnosis."
01/01/2017 - "The analyzed markers in this study can be used to quantify the degree of collagen sclerosis from the ECM of DCM."
06/01/2005 - "The histological study of two patients revealed a variable degree of collagen alteration (sclerosis and hyalinization). "
03/01/1988 - "Ultrastructural study demonstrated that the tubular sclerosis was due to collagen deposition by fibromyocytes in the peritubular sheath. "

01/01/2014 - "Meanwhile, serum creatinine and urea levels as well as glomerular sclerosis and tubulointerstitial injury indexes were decreased at 4 and 8 weeks. "
09/01/1990 - "In 6 wk, young rats developed more pronounced glomerular sclerosis and more marked elevation in blood urea nitrogen. "
12/01/1985 - "Sclerosis with quinine-urea is indicated in this situation. "
03/01/1999 - "Here we examined the effects of carbamylated proteins on glomerular mesangial cells to determine whether urea retention in early renal insufficiency may itself promote glomerular sclerosis and hasten the progression to kidney failure. "
01/01/2018 - "These mice were treated with a small molecule inhibitor selective for LOXL2 or with vehicle and assessed for glomerular sclerosis and fibrosis, albuminuria, blood urea nitrogen, lifespan, pro-fibrotic gene expression and ultrastructure of the glomerular basement membrane. "

08/08/2022 - "Rituximab, an anti-CD20 antibody, showed improvement in both modified Rodnan skin score, a measure of skin sclerosis, and FVC in the DESIRES study, and was approved in Japan for the treatment of SSc itself. "
07/01/2021 - "Although this study has some limitations, this is the first clinical trial to show efficacy of rituximab with skin sclerosis as the primary endpoint. "
08/01/2022 - "The Role of Rituximab in Primary Focal Segmental Glomerular Sclerosis of the Adult."
01/01/2022 - "Az első B-sejt-depletáló, anti-CD20 monoklonális antitest a rituximab volt, amit sclerosis multiplexben is vizsgáltak, és a kedvező eredményeket követően újabb gyógyszerek kerültek kifejlesz­tésre, hasonló támadásponttal. "
04/01/2007 - "Treatment of focal segmental glomerular sclerosis with rituximab: 2 case reports."

03/01/1995 - "In all patients, the levels decreased to the normal range after oral corticosteroid treatment, and skin sclerosis improved. "
01/01/2022 - "Later Response to Corticosteroids in Adults With Primary Focal Segmental Glomerular Sclerosis Is Associated With Favorable Outcomes."
01/01/1990 - "Histologically, cases in which the sum of the proportions of glomeruli affected with segmental sclerosis and with global sclerosis exceeded 30% and, in addition, there were severe tubulointerstitial lesions tended to have a poor prognosis, while those in which sclerosis involved less than 30% of glomeruli and no interstitial damage was discernible had a relatively favorable prognosis and were more frequently responsive to corticosteroids. "
05/01/1978 - "[Long-term corticoid treatment of disseminated cerebrospinal sclerosis]."
05/01/2019 - "MRI study of Baló's concentric sclerosis before and after corticosteroid therapy."

12/14/2019 - "We study the prevalence of AS, aortic valve calcification (AoVC), and aortic sclerosis (ASc) in elderly subjects with HeFH in a prolonged statin treatment. "
01/01/2011 - "In total, 33 patients (18 males, 15 females; mean age 70 +/- 8 years) with aortic sclerosis or mild AS, who had never received statin treatment, were enrolled into the study. "
12/01/2018 - "Statins Have No Role in Preventing the Progression of Aortic Valve Sclerosis."
03/01/2016 - "The Effect of HMG CoA Reductase Inhibitors on the Progression of Aortic Sclerosis: Review Article."
03/01/2011 - "Statin treatment of hypercholesterolemic-induced aortic valve sclerosis."

07/01/2008 - "Glomerular sclerosis of diverse etiologies is characterized by mesangial matrix accumulation, with transforming growth factor-beta (TGFbeta) an important pathogenic factor. "
11/01/1999 - "Although the pathogenic relevance of transforming growth factor-beta (TGF-beta) to glomerular sclerosis has been established, the intracellular mechanisms by which TGF-beta induces extracellular matrix accumulation are not fully understood. "
08/01/1998 - "TGF-beta, but not PDGF, also changed the quality of the de novo synthesized FN, and thus has a different role in the development of sclerosis."
01/01/1998 - "TGF beta is important in the subsequent development of sclerosis. "
04/01/1997 - "Our results suggest that stretch-induced TGF-beta of mesangial cells might be a mediator in the progression of glomerular sclerosis as an autocrine/paracrine factor."

08/01/2023 - "Focal segmental glomerular sclerosis can be effectively treated using an intensive B-cell depletion therapy."
07/01/1985 - "Crossectomy and a stripping operation, on the one hand, plus sclerosis therapy on the other are emphasized as complementary non-competing measures in the therapeutic treatment of varicosis of the great saphenous system. "
01/01/2022 - "The drug has also recently been approved by the EMA in March 2021 for use in relapsing forms of MS. In this review, we detail the mechanism of action and efficacy of anti-CD20 therapies currently used in MS. Az elmúlt évek kutatási eredményei bizonyították, hogy a B-lymphocyták döntő szerepet játszanak a sclerosis multiplex (SM) patogenezisében. "
01/01/2011 - "Durometry proved to be helpful in assessing the degree of sclerosis and in documenting the response to therapy in these patients."
11/01/1996 - "The prevention of progressive glomerular sclerosis following DFO therapy might be associated with an improvement in early glomerular in filtration of M phi."

01/01/1999 - "Following 4 cycles of chemotherapy, he had complete remission and the skin sclerosis remarkably improved. "
06/01/2011 - "Local (intrapericardial) chemotherapy has been reported to be useful for the treatment of neoplastic pericardial disease, but it has never been compared to systemic chemotherapy, a combination of the two and simple pericardial drainage or sclerosis. "
06/01/1994 - "Factors that predicted shorter remission duration in a multivariate analysis were nodular sclerosis histology, bulky disease, and receipt of less than 85% of planned chemotherapy. "
04/17/2024 - "Robotic biliary stricturoplasty with RY hepaticojejunostomy for treatment of biliary sclerosis after HAIP chemotherapy is safe and feasible. "
01/01/2022 - "These results may help future holistic programming for individuals with MS incorporate behavioral interventions with therapeutic rehabilitation to increase physical activity adherence.IMPLICATIONS FOR REHABILITATIONMultiple sclerosis is a neurological disease impacting physical and cognitive functioning that may be managed with a combination of drug therapies, rehabilitation, and physical activity.Individuals"

01/01/2020 - "Radiotherapy to any lesions could independently improve the OS and CSS by 30% to 36% in the multivariate analyses before and after PS matching (PSM), with the best improvement of 33% to 40% observed for patients with nodular sclerosis (P < 0.05) among all HL pathological types. "
11/15/1999 - "In patients with PMLBCL with sclerosis, MACOP-B plus radiation therapy is a very useful first-line treatment and radiation therapy may play an important role. "
12/01/1975 - "extended field regional radiotherapy only, resulted in a long first complete remission period in lymphocyte predominance and nodular sclerosis H.D. "
08/01/2014 - "Mandibular condyle erosion and sclerosis in pediatric patients treated with radiotherapy to the head and neck region."
01/01/2008 - "Glomerular hypercellularity, crescents, global sclerosis and tubulointerstitial damage developed gradually in Group II rats, but were decreased (p < 0.05 or 0.001) after radiation treatment. "

01/01/1995 - "The osteopetrotic (op) mutation in mice is characterized by general skeletal sclerosis; reduced numbers of osteoclasts, macrophages, and monocytes; and failure to be cured by bone marrow transplantation. "
09/01/2006 - "Prevention of mesangial sclerosis by bone marrow transplantation."
02/01/2006 - "Bone marrow transplantation can attenuate the progression of mesangial sclerosis."
12/01/2001 - "X-ray confirmed attenuation of the bone sclerosis; therefore, bone marrow transplantation (BMT) was not implemented. "
02/01/1989 - "Bone marrow transplantation, originally shown to reverse the skeletal sclerosis in some animal mutations, has been effective in curing osteopetrosis in some children. "

01/01/1998 - "Emphasis is laid on the positive results of application of puncture-aspiration method with ensuing sclerosis, carried out under intraoperative echographic monitoring."
09/01/1992 - "The most striking findings in the micropuncture studies were a significant increase of glomerular capillary pressure in group IV rats (63.15 +/- 1.34 mm Hg) as compared to controls (48.74 +/- 0.97 mm Hg) and to groups II and III (55.31 +/- 2.11 and 48.17 +/- 1.23 mm Hg, respectively), and a marked fall in Kf in groups III and IV. Only group IV showed significant histological alterations such as glomerular sclerosis, interstitial damage, and increased glomerular area. "
05/01/1993 - "In puncture liver biopsies, sclerosis of walls of big ducts and portal tracts was found in 2 cases only; cell infiltration was minimal. "
07/01/1988 - "Serial micropuncture analysis of glomerular function in two rat models of glomerular sclerosis."
04/01/1985 - "Without mistaking the role of complementary sclerosis in these cases, they affirm that reliable results are more difficult to obtain with this sort of vein and they suggest peroperative puncture phlebectomy as the results of this seem very encouraging."