Oxytetracycline (Terramycin)

A TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES RIMOSUS and used in a wide variety of clinical conditions.

Also Known As:

Terramycin; Bisolvomycin; Geomycin; Oxyterracin; Oxyterracine; Oxytetracid; Oxytetracycline Anhydrous; Oxytetracycline Calcium; Oxytetracycline Dihydrate; Oxytetracycline Hydrochloride; Oxytetracycline Monohydrochloride; Oxytetracycline Sulfate (2:1); Oxytetracycline, (4a beta,5 beta,5a beta,12a beta)-Isomer; Oxytetracycline, (5 beta)-Isomer; Oxytetracycline, Anhydrous; Oxytetracycline, Calcium (1:1) Salt; Oxytetracycline, Disodium Salt, Dihydrate; Oxytetracycline, Sodium Salt; Hydroxytetracycline; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6beta,12aalpha))-

Networked: 1377 relevant articles (94 outcomes, 134 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Lees, P: 4 articles (10/2017 - 09/2012)
2.	Wang, Lei: 3 articles (10/2022 - 02/2014)
3.	Coetzee, Johann F: 3 articles (11/2021 - 01/2005)
4.	Larsen, Inge: 3 articles (01/2017 - 01/2016)
5.	Nielsen, Jens Peter: 3 articles (01/2017 - 01/2016)
6.	Olsen, John Elmerdahl: 3 articles (01/2017 - 01/2016)
7.	Booker, Calvin W: 3 articles (01/2009 - 05/2002)
8.	Jim, G Kee: 3 articles (01/2009 - 05/2002)
9.	Wildman, Brian K: 3 articles (01/2009 - 05/2002)
10.	Patil, Prasanna Kumar: 2 articles (02/2024 - 01/2022)

Related Diseases

1.	Infections 05/01/1986 - "Neither compound showed prophylactic properties even though both are effective in extending the prepatent period and, in the case of oxytetracycline, reducing the severity of infection." 01/01/1986 - "Gram-negative bacteria predominate, and oxytetracycline is effective in treatment of infections induced by them. " 10/01/1983 - "Studies on the use of a long-acting oxytetracycline in turkeys: efficacy against experimental infections with Alcaligenes faecalis and Pasteurella multocida." 02/01/2016 - "The efficacy of oxytetracycline treatment at batch, pen and individual level on Lawsonia intracellularis infection in nursery pigs in a randomised clinical trial." 01/01/2007 - "Lack of resistance after re-exposure of cattle cured of Onchocerca ochengi infection with oxytetracycline."
2.	Anaplasmosis 09/01/1978 - "Efficacy of a new oxytetracycline formulation against clinical anaplasmosis." 01/01/1979 - "Efficacy of terramycin/LA-200 administered during the prepatent period of anaplasmosis." 01/01/1991 - "The objective of this study was to test the efficiency and acceptability of oxytetracycline hydrochloride (OTC) in anaplasmosis. " 11/15/1958 - "Laboratory studies of anaplasmosis in cattle treated with oxytetracycline." 11/20/2021 - "Oxytetracycline, administered by injection, is indicated for treatment of clinical anaplasmosis in beef and dairy cattle and calves. "
3.	Digital Dermatitis 04/01/2000 - "A field trial was conducted to compare the efficacy of the original and two modified formulations of Victory and oxytetracycline among dairy cows affected with papillomatous digital dermatitis. " 04/15/2000 - "Efficacy of oxytetracycline for treatment of papillomatous digital dermatitis lesions on various anatomic locations in dairy cows." 04/01/2000 - "The 2 low efficacy of oxytetracycline was an unexpected result b and may have clinical implications associated with possible antibiotic resistance in dairy cows affected with papillomatous digital dermatitis." 11/08/2008 - "Healing of digital dermatitis after a single treatment with topical oxytetracycline in 89 dairy cows." 03/01/1999 - "Comparison of topical application of oxytetracycline and four nonantibiotic solutions for treatment of papillomatous digital dermatitis in dairy cows."
4.	Fever (Fevers) 12/01/2002 - "An evaluation of the relative efficacy of a new formulation of oxytetracycline for the treatment of undifferentiated fever in feedlot calves in western Canada." 04/07/1990 - "Efficacy of long-acting oxytetracycline for the prevention of tick-borne fever in calves." 04/07/1990 - "At the end of the trial the treated group weighed on average 16 kg more than the control group, a difference which was attributed to the suppression of tick-borne fever by oxytetracycline." 09/01/1956 - "[Study on the use of terramycin in the treatment of Spanish recurrent fever]." 11/15/1996 - "To establish the maximum concentration and duration of oxytetracycline residues in milk from cows with retained fetal membranes given the antimicrobial via intrauterine infusion, and to investigate whether the number of infusions or the presence of fever (> 39.7 C) affected the duration of residues. "
5.	Body Weight (Weight, Body) 07/27/2020 - "Therefore, this study was conducted to evaluate the pharmacokinetic profile of the oxytetracycline long-acting formulation (OTC-LA) in the freshwater crocodile, Crocodylus siamensis, following a single intramuscular (i.m.) administration at three different dosages of 5, 10 and 20 mg/kg body weight (b.w.). " 04/01/2017 - "The present study aimed to characterize the pharmacokinetic profile of oxytetracycline long-acting formulation (OTC-LA) in Thai swamp buffaloes, Bubalus bubalis, following single intramuscular administration at two dosages of 20 and 30 mg/kg body weight (b.w.). " 04/01/2011 - "The penetration of oxytetracycline (OTC) in plasma and nasal secretions of healthy pigs was evaluated during the first study, in response to oral dose of 20 mg of OTC per kg of body weight (bwt) per day as a 400 mg/kg feed medication (n = 5) and to intramuscular (i.m.)-administered formulations at 10 mg/kg bwt (n = 5), 20 mg/kg bwt (n = 5), 40 mg/kg bwt (n = 5). " 02/01/2011 - "The purpose of this study was to investigate the hemolymph kinetics and depuration time of oxytetracycline following intramuscular administration at doses of 2, 8 and 40 mg/kg body weight, respectively. " 12/01/1990 - "In both trials each piglet received an i/v-injection of oxytetracycline (dosage 10 mg/kg body weight) and an oral dose of oxytetracycline (40 mg/kg body weight). "

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Doxycycline (Periostat)
3.	Chlortetracycline (Aureomycin)
4.	Tetracycline (Achromycin)
5.	Enrofloxacin
6.	Hydrocortisone (Cortisol)
7.	Penicillins (Penicillin)
8.	florfenicol
9.	Streptomycin (Streptomycin Sulfate)
10.	tilmicosin

Related Therapies and Procedures

1.	Therapeutics
2.	Intramuscular Injections
3.	Injections
4.	Aftercare (After-Treatment)
5.	Operative Surgical Procedures