Econazole

An imidazole derivative that is commonly used as a topical antifungal agent.

Also Known As:

Econazole Nitrate; Ekonazole; Gyno-Pervaryl 150; Gyno-Pevaril; Gyno-Pevaryl; Pevaryl; Gyno Pervaryl 150; Gyno Pevaril; Gyno Pevaryl; GynoPevaril; Nitrate, Econazole; 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-

Networked: 210 relevant articles (28 outcomes, 47 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 207
- 1-Ring Heterocyclic Compounds
  - Azoles: 2199
    - Imidazoles: 152
      - Econazole: 210
        Pevisone: 3
        econazole sulfosalicylate

Experts

1.	Ahmad, Zahoor: 4 articles (02/2008 - 05/2006)
2.	Sharma, Sadhna: 4 articles (02/2008 - 05/2006)
3.	Jan, Chung-Ren: 3 articles (07/2023 - 09/2005)
4.	Chen, Ceshi: 3 articles (01/2022 - 12/2017)
5.	Dong, Chao: 3 articles (01/2022 - 12/2017)
6.	Ke, Kunbin: 3 articles (01/2022 - 12/2017)
7.	Li, Hongjian: 3 articles (01/2022 - 12/2017)
8.	Lin, Marie Chia-Mi: 3 articles (01/2022 - 12/2017)
9.	Luo, Chunxiang: 3 articles (01/2022 - 12/2017)
10.	Yang, Runxiang: 3 articles (01/2022 - 12/2017)

Related Diseases

1.	Candidiasis (Moniliasis) 01/01/1979 - "Pointing out the fact that there is a generalized increase in the incidence of vaginal candidiasis the authors describe a study involving a total of sixty-one patients to evaluate econazole in the treatment of the condition." 01/15/2018 - "The purpose of this work was to prepare and characterize an innovative formulation for vaginal delivery of econazole nitrate, commonly used for the treatment of Candida infections. " 12/01/2015 - "Although econazole is among the most frequently used topical formulations for the treatment of candidiasis, no information is available regarding the susceptibility profiles of Candida species in Iran. " 01/01/2014 - "This synergistic effect may markedly reduce the dose of econazole-nitrate required to treat candidiasis, thereby decreasing the econazole-nitrate toxic side effects. " 10/01/2011 - "By careful engineering of the rheological properties, in-situ thermosensitive gel formulations of econazole nitrate were prepared and were shown to be efficacious in the treatment of vaginal candidiasis."
2.	Infections 04/01/1990 - "The antibacterial efficacy of econazole nitrate in interdigital toe web infections." 11/25/2023 - "The purpose of this work was to develop a novel topical formulation of econazole nitrate based on gel that can be easily scaled up in one pot for the potential treatment of fungal and yeast infections. " 01/01/2022 - "Finally, mouse infection models were used to detect the ability of econazole on killing the tolerant populations in vivo. " 05/11/2018 - "The eluted econazole demonstrated bioactivity in a concentration-dependent manner against the most common species responsible for fungal periprosthetic joint infection as well as staphylococci. " 05/11/2018 - "Econazole-releasing porous space maintainers for fungal periprosthetic joint infection."
3.	Otomycosis 04/01/1978 - "Econazole (1 % milk) would appear to be the drug of choice in the treatment of otomycoses of the E.A.M., being effective against the fungi usually responsible (Aspergillus niger, fumigatus, flavus, Candida albicans, krusei etc.), as well as having a bactericidal action against Gram + bacteria." 04/01/1978 - "The authors studied the effectiveness and tolerance of Econazole (1 % milk) in the treatment of otomycoses. " 07/01/1976 - "[Report on 27 patients with otomycosis treated with the antimycotic econazole 1% lotion]." 08/01/1986 - "Econazole 1 per cent solution was very effective in vivo in the treatment of otomycosis within 1-3 weeks. " 07/01/2015 - "[Clinical analysis of external ear canal coating by otoendoscopy on otomycosis external with triamcinolone acetonide and econazole nitrate cream]."
4.	Tinea Pedis (Athlete's Foot) 11/01/1990 - "This study was conducted to determine the efficacy of twice-daily applications of econazole nitrate 1% for the treatment of tinea pedis within a typical podiatric practice. " 11/01/1990 - "Efficacy of twice-daily dosing of econazole nitrate 1% cream for tinea pedis." 07/01/2014 - "Econazole nitrate foam 1% for the treatment of tinea pedis: results from two double-blind, vehicle-controlled, phase 3 clinical trials." 09/01/2016 - "Econazole nitrate topical foam, 1%, is indicated for the treatment of interdigital tinea pedis caused by <em>Trichophyton rubrum, Trichophyton mentagrophytes,</em> and <em>Epidermophyton floccosum</em> in patients 12 years of age and older. " 09/01/2016 - "Econazole Nitrate Foam 1% Improves the Itch of Tinea Pedis."
5.	Tinea (Ringworm) 05/01/1983 - "Econazole was found to be a very potent drug in the management of dermatophytosis." 12/01/1984 - "A double-blind parallel study comparing sulconazole with econazole in the treatment of dermatophytoses." 09/01/2016 - "Cats, suffering from the most widely spread Microsporum canis-induced dermatophytosis and treated with terbinafine hydrochloride 1% cream, recovered within 20.3±0.88 days; whereas when treated with econazole nitrate 1% cream, they recovered within 28.4±1.14 days. " 05/01/1983 - "Comparative Study of Econazole and Povidone Iodine (betanide) in Management of Dermatophytosis." 12/01/1980 - "Clotrimazole and econazole in dermatophytoses (double blind study)."

Related Drugs and Biologics

1.	Clotrimazole (Lotrimin)
2.	Ketoconazole (Nizoral)
3.	Itraconazole (Sporanox)
4.	Miconazole (Monistat)
5.	Econazole
6.	Terbinafine (Lamisil)
7.	naftifine (naftifine hydrochloride)
8.	Triamcinolone Acetonide (Azmacort)
9.	Solutions
10.	Voriconazole (Vfend)

Related Therapies and Procedures

1.	Therapeutics
2.	Oral Administration
3.	Aftercare (After-Treatment)
4.	Drug Therapy (Chemotherapy)
5.	Contact Lenses