Naloxone Drug Combination Buprenorphine

A pharmaceutical preparation that combines buprenorphine, an OPIOID ANALGESICS with naloxone, a NARCOTIC ANTAGONISTS to reduce the potential for NARCOTIC DEPENDENCE in the treatment of pain. It may also be used for OPIOID SUBSTITUTION THERAPY.

Also Known As:

Buprenorphine, Naloxone Drug Combination; Buprenorphine Naloxone; Buprenorphine Naloxone Drug Combination; Buprenorphine-Naloxone; Buprenorphine-Naloxone Combination; Buprenorphine-Naloxone Drug Combination; Suboxone; Buprenorphine Naloxone Combination; Combination, Buprenorphine-Naloxone; Combination, Buprenorphine-Naloxone Drug; Drug Combination, Buprenorphine-Naloxone; Naloxone, Buprenorphine

Networked: 564 relevant articles (81 outcomes, 116 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Fiellin, David A: 22 articles (12/2020 - 09/2004)
2.	Ling, Walter: 21 articles (06/2022 - 01/2004)
3.	Rotrosen, John: 18 articles (11/2023 - 01/2012)
4.	Jutras-Aswad, Didier: 16 articles (05/2024 - 01/2018)
5.	Le Foll, Bernard: 16 articles (05/2024 - 01/2018)
6.	Nunes, Edward V: 14 articles (11/2023 - 11/2016)
7.	Lim, Ron: 12 articles (05/2024 - 01/2018)
8.	Socias, M Eugenia: 12 articles (04/2024 - 01/2018)
9.	Weiss, Roger D: 12 articles (08/2020 - 03/2010)
10.	Griffin, Margaret L: 11 articles (08/2020 - 03/2010)

Related Diseases

1.	Opioid-Related Disorders (Opiate Addiction) 01/01/2019 - "Screening for opioid use disorder in the ED and initiating buprenorphine/naloxone treatment with rapid referral to an outpatient community-based addictions clinic led to a 6-month treatment retention rate of 37% and a significant reduction in ED visits at 3 and 6 months. " 07/27/2006 - "Among patients receiving buprenorphine-naloxone in primary care for opioid dependence, the efficacy of brief weekly counseling and once-weekly medication dispensing did not differ significantly from that of extended weekly counseling and thrice-weekly dispensing. " 01/01/2023 - "Background: Although buprenorphine/naloxone has been demonstrated to be an effective treatment for patients with opioid use disorder (OUD), treatment retention has been a challenge. " 01/01/2023 - "Buprenorphine/naloxone has been shown to be effective for treating opioid use disorder (OUD). " 05/01/2022 - "Buprenorphine/naloxone is an effective medication for the treatment of opioid use disorder. "
2.	Substance Withdrawal Syndrome (Withdrawal Symptoms) 06/01/2023 - "The patient was successfully treated with buprenorphine/naloxone, which helped alleviate his withdrawal symptoms and allowed him to abstain from kratom. " 12/14/2023 - "He was initially managed with buprenorphine/naloxone and supportive care and reported improvement in withdrawal symptoms within three days of admission. " 12/14/2023 - "He was initially managed with buprenorphine/naloxone and supportive care and reported improvement in withdrawal symptoms within three days of admission. " 12/01/2019 - "Study outcomes were based on presence of withdrawal symptoms, instances of unauthorized substances in urine drug tests (UDTs), and sublingual buprenorphine/naloxone (SBN) dose with standard-of-care (SOC) dosing versus pharmacogenomics (PGx)-based dosing. " 11/01/2018 - "Her kratom-related withdrawal symptoms responded to a trial of buprenorphine-naloxone. "
3.	Pain (Aches) 01/01/2021 - "After initiating buprenorphine-naloxone, the patient reported rapid improvement in depressive symptoms, pain, and suicidal ideation. " 04/01/2022 - "Little is known about changes in pain during buprenorphine/naloxone (BUP/NX) maintenance and whether outcomes vary by pain levels. " 03/02/2021 - "Data gathered include psychiatric diagnoses, prescribed medications, pain score, buprenorphine/naloxone dosing, time in clinic, and reason for dismissal. " 03/01/2020 - "In this case series, the authors explore the frequency of buprenorphine-naloxone use and its outcomes in patients in a Compre-hensive Care Center (CCC) Pain Registry. " 01/01/2020 - "Pain was preceded by self-injection of dissolved buprenorphine/naloxone sublingual film onto the affected arm. "
4.	Chronic Pain 01/01/2022 - "Buprenorphine/naloxone has unique pharmacological properties that are beneficial in chronic pain treatment. " 01/01/2024 - "This study is a retrospective case series that included all patients who received care at an outpatient chronic pain clinic and were scheduled for low-dose initiation of buprenorphine/naloxone between March 2020 and December 2022. " 01/01/2023 - "In this qualitative pilot study, 21 patients who were hospitalized for rotation to buprenorphine/naloxone as agonist treatment for chronic pain and OUD were offered MBCT. " 03/02/2021 - "Sublingual Buprenorphine/Naloxone and Multi-Modal Management for High-Risk Chronic Pain Patients." 01/15/2020 - "Rapid Induction of Buprenorphine/Naloxone for Chronic Pain Using a Microdosing Regimen: A Case Report."
5.	Cancer Pain 01/01/2023 - "Furthermore, buprenorphine-naloxone is a safe and effective option to simultaneously manage kratom withdrawal and cancer-associated pain." 03/01/2020 - "Given its success at the CCC, buprenorphine-naloxone should be made available and strongly considered as a treatment for patients suffering from OUD during and following cancer treatment and when cancer pain re-duces or resolves." 03/01/2020 - "Of 2,320 chronic cancer pain patients, 125 patients had ICD-10 code for opioid-related disorders, and 43 had a diagnosis of opioid abuse of whom 11 received buprenorphine-naloxone combina-tions. " 12/01/2012 - "This retrospective chart review reports results of a quality improvement project using buprenorphine/naloxone to treat co-occurring chronic non-cancer pain (CNCP) and opioid dependence in a primary care setting. " 12/01/2021 - "A 3-round modified Delphi process was completed from August to October 2020 with 2 cases: patient with advanced cancer, pain, and OUD treated with buprenorphine-naloxone or methadone. "

Related Drugs and Biologics

1.	Buprenorphine (Subutex)
2.	Opioid Analgesics (Opioids)
3.	Methadone (Dolophine)
4.	Narcotic Antagonists (Opioid Antagonists)
5.	Naloxone Drug Combination Buprenorphine
6.	Naltrexone (ReVia)
7.	Tablets
8.	Naloxone (Narcan)
9.	trans-crotonin (CTN)
10.	Heroin (Diamorphine)

Related Therapies and Procedures

1.	Therapeutics
2.	Opiate Substitution Treatment
3.	Drug Substitution
4.	Glycemic Control
5.	Drug Therapy (Chemotherapy)