Abstract |
Feldamycin, a new antibacterial agent, and nojirimycin, a previously described antibiotic have been isolated from cultures of Streptomyces ficellus. Feldamycin, C17H25N7O5, is an amphoteric compound which inhibits a variety of bacteria in vitro but is found to be ineffective in the treatment of experimental bacterial infections in mice. Nojirimycin (5-amino-5-deoxy-D-glucose) has been isolated previously from cultures of several species of streptomycetes.
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Authors | A D Argoudelis, F Reusser, S A Mizsak, L Baczynskyj |
Journal | The Journal of antibiotics
(J Antibiot (Tokyo))
Vol. 29
Issue 10
Pg. 1007-14
(Oct 1976)
ISSN: 0021-8820 [Print] England |
PMID | 994320
(Publication Type: Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Antibiotics, Antineoplastic
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Topics |
- Animals
- Anti-Bacterial Agents
(analysis, biosynthesis, pharmacology)
- Antibiotics, Antineoplastic
(therapeutic use)
- Bacterial Infections
(prevention & control)
- Chemical Phenomena
- Chemistry
- Fermentation
- Fungi
(drug effects)
- Leukemia L1210
(drug therapy)
- Mice
- Streptomyces
(metabolism)
- Viruses
(drug effects)
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