[Feto-maternal transfusion following cordocentesis].
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| Abstract |
Invasive intrauterine diagnostic procedures may be followed by feto-maternal transfusion. The authors studied the feto-maternal transfusion after cordocentesis. 199 women underwent fetal umbilical cord blood sampling for fetal karyotyping in weeks 15-26. Maternal serum alpha-fetoprotein level was measured before and after the procedure. The data were statistically analysed by multiple regression analysis and the paired and unpaired Student's t-tests. Twenty percent of more maternal serum alpha-fetoprotein level increase was observed in 73 (36.7%) women. Maximum feto-maternal transfusion was 0.684 ml. The average feto-maternal transfusion was 0.045 ml. No fetal exsanguination was observed. Positive correlation was found between bleeding time after cordocentesis (p = 0.0171) and feto-maternal transfusion as well as the duration of the procedure (p = 0.0275) and feto-maternal transfusion. Negative correlation was found between the amount of fetal blood sample and feto-maternal transfusion (p = 0.0431). The puncture site also influenced feto-maternal transfusion. If the cordocentesis has been performed at the insertion of the cord the feto-maternal transfusion was less than at the free floating umbilical cord (p = 0.0293). Higher feto-maternal transfusion was seen more often after transplacental cordocentesis (p = 0.002). These data suggest that fetomaternal transfusion in the indicator of the difficulty of the procedure.
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| Authors | J Sikovanyecz, T Nyári, M Faragó, E Sallay, J Gellén, J Szabó |
| Journal | Orvosi hetilap (Orv Hetil) Vol. 139 Issue 35 Pg. 2059-64 (Aug 30 1998) ISSN: 0030-6002 [Print] Hungary |
| Vernacular Title | Foetomaternalis transzfúzió cordocentesis kapcsán. |
| PMID | 9755624 (Publication Type: English Abstract, Journal Article) |
| Chemical References |
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| Topics |
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