Disseminated coccidioidomycosis associated with hypercalcemia.

Abstract

This article describes a patient in whom disseminated infection with coccidioidomycosis was associated with hypercalcemia. The patient had a low level of 1,25-dihydroxyvitamin D and a suppressed parathyroid hormone value, an indication that the hypercalcemia was not mediated by vitamin D or parathyroid hormone. The episode resolved readily with administration of pamidronate, an outcome suggesting that this is effective treatment of hypercalcemia of this origin. On follow-up of the patient while he was receiving antifungal therapy for Coccidioides immitis, calcium values remained normal.

• Authors: S A Westphal
• Journal: Mayo Clinic proceedings (Mayo Clin Proc) Vol. 73 Issue 9 Pg. 893-4 (Sep 1998) ISSN: 0025-6196 [Print] England
• PMID: 9737228 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antifungal Agents
• Diphosphonates
• Pamidronate

Topics

• Adult
• Antifungal Agents (therapeutic use)
• Bone and Bones (drug effects)
• Coccidioidomycosis (complications, drug therapy)
• Diphosphonates (therapeutic use)
• Humans
• Hypercalcemia (drug therapy, microbiology)
• Male
• Pamidronate