[Leriche syndrome: treatment with local lysis and subsequent percutaneous transluminal angioplasty].

Abstract

Two cases of Leriche's syndrome treated by local thrombolysis and subsequent percutaneous transluminal angioplasty with or without additional stent implantation are described. The fibrinolytic drugs were applied locally into the occlusions through a Mewissen Infusion Catheter and a Katzen Infusion Wire (initial 2.5 mg rt-PA as bolus followed by Urokinase (50000 IU/h) during 24 and 48 hours respectively. Residual stenotic lesions and occlusions were successfully treated with PTA alone in case 1 and with PTA in combination with a stent implantation in case 2. In accordance with Bean et al. (1985) and Goffette et al. (1989) we recommend local lysis in combination with PTA with or without additional stent implantation as an alternative treatment to surgery or systemic lysis for the treatment of Leriche's syndrome.

• Authors: R Katzenschlager, A Ahmadi, R Koppensteiner, E Minar, A Stümpflen, A Ugurluoglu, H Ehringer
• Journal: VASA. Zeitschrift fur Gefasskrankheiten (Vasa) Vol. 25 Issue 2 Pg. 180-3 ( 1996) ISSN: 0301-1526 [Print] Switzerland
• Vernacular Title: Leriche-Syndrom: Behandlung mit lokaler Lyse und anschliessender perkutaner transluminaler Angioplastie.
• PMID: 8659222 (Publication Type: Case Reports, Journal Article)

Chemical References

• Recombinant Proteins
• Tissue Plasminogen Activator
• Urokinase-Type Plasminogen Activator

Topics

• Adult
• Angiography, Digital Subtraction
• Angioplasty, Balloon
• Aortography
• Combined Modality Therapy
• Humans
• Leriche Syndrome (diagnostic imaging, therapy)
• Male
• Recombinant Proteins (administration & dosage)
• Stents
• Thrombolytic Therapy
• Tissue Plasminogen Activator (administration & dosage)
• Urokinase-Type Plasminogen Activator (administration & dosage)