Abstract |
Ribosomal protein L18 mRNA is overexpressed in human colorectal cancer compared to normal colon tissue. We report the nucleotide sequence of human L18 cDNA derived from a normal colon source. There were no mutational changes in segments of L18 cDNA derived from two tumor sources. The L18 cDNA was 690 base pairs long and predicts a single open reading frame of 564 nucleotides, encoding 188 amino acids with a M(r) = 21,621, it is homologous to rat L18 and Xenopus laevis L14.
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Authors | M Puder, G F Barnard, R J Staniunas, G D Steele Jr, L B Chen |
Journal | Biochimica et biophysica acta
(Biochim Biophys Acta)
Vol. 1216
Issue 1
Pg. 134-6
(Oct 19 1993)
ISSN: 0006-3002 [Print] Netherlands |
PMID | 8218404
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- DNA, Complementary
- RNA, Messenger
- Ribosomal Proteins
- ribosomal protein L18
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Topics |
- Amino Acid Sequence
- Base Sequence
- Colon
(metabolism)
- Colorectal Neoplasms
(genetics)
- DNA, Complementary
(chemistry)
- Gene Expression
- Gene Library
- Humans
- Molecular Sequence Data
- RNA, Messenger
(isolation & purification)
- Ribosomal Proteins
(genetics)
- Sequence Homology, Nucleic Acid
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