Abstract |
The incidence of postoperative bronchopneumonia in 70 patients undergoing upper abdominal surgery who received intramuscular and oral bromhexine after operation for 5 days was 25% (8 of 32), compared with 34% (13 of 38) in a control group, but this difference in favour of bromhexine does not reach statistical significance. All patients had postoperative physiotherapy. However, in a high-risk group (patients who smoked more than 10 cigarettes a day, who admitted to a productive cough before the operation and in whom the forced expiratory volume as a percentage of the forced vital capacity was less than 70) the incidence of postoperative bronchopneumonia in those who had bromhexine was 6 of 17 compared with 9 of 15 in the controls. Thus bromhexine for the prevention and treatment of postoperative bronchopneumonia in high-risk patients after upper abdominal surgery deserves further study.
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Authors | S A Hargrave, K N Palmer, E J Makin |
Journal | British journal of diseases of the chest
(Br J Dis Chest)
Vol. 69
Pg. 195-8
(Jul 1975)
ISSN: 0007-0971 [Print] England |
PMID | 811237
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Adult
- Aged
- Biliary Tract Surgical Procedures
- Bromhexine
(administration & dosage, therapeutic use)
- Bronchitis
(complications, drug therapy)
- Bronchopneumonia
(epidemiology, prevention & control)
- Female
- Forced Expiratory Volume
- Gastrectomy
- Humans
- Male
- Middle Aged
- Physical Therapy Modalities
- Postoperative Care
- Postoperative Complications
(epidemiology, prevention & control)
- Smoking
(complications)
- Vital Capacity
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