[The combined-action preparation Sipralinat in the treatment of suppurative diseases of the soft tissues and osteomyelitis of the bones of the foot].

Abstract

Sipralynate is a powder containing the broad spectrum antibiotic sisomicin, the enzyme protease C and the polymer carrier sodium alginate with a drainage capacity promoting wound regeneration. The clinical trials with sipralynate showed that it was highly efficient in the treatment of patients with suppurative infections of the soft tissues and ossa pedis osteomyelitis. The tolerance was good.

• Authors: Z F Vasil'kova, A G Khanin, M G Kachakhidze, I M Romanchenko, E V Kagan, V P Pozdniakova
• Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] (Antibiot Khimioter) 1994 Feb-Mar Vol. 39 Issue 2-3 Pg. 61-3 ISSN: 0235-2990 [Print] Russia (Federation)
• Vernacular Title: Preparat kombinirovannogo deĭstviia Sipralinat v lechenii gnoĭnykh zabolevaniĭ miagkikh tkaneĭ i osteomielita kosteĭ stopa.
• PMID: 7979799 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Alginates
• Drug Carriers
• Drug Combinations
• Hexuronic Acids
• Powders
• Sipralinat
• Glucuronic Acid
• Serine Endopeptidases
• protease C
• Calcium Gluconate
• Sisomicin

Topics

• Administration, Topical
• Adult
• Aged
• Aged, 80 and over
• Alginates (therapeutic use)
• Calcium Gluconate (therapeutic use)
• Drug Carriers
• Drug Combinations
• Drug Evaluation
• Female
• Foot Diseases (drug therapy, microbiology)
• Glucuronic Acid
• Hexuronic Acids
• Humans
• Male
• Middle Aged
• Osteomyelitis (drug therapy, microbiology)
• Powders
• Serine Endopeptidases (therapeutic use)
• Sisomicin (therapeutic use)
• Soft Tissue Infections (drug therapy, microbiology)