[Passive immunotherapy with Venimmun for the prevention of habitual abortion--early pregnancy factor, placenta protein 12, placenta protein 14, tumor necrosis factor alpha--parameters for monitoring immunotherapy].

Abstract	In a study it was investigated to what extent the early pregnancy factor, the placental proteins 12 and 14 and tumor necrosis factor alpha are suited to control and select patients with habitual abortions for immunotherapy. Immunotherapy shows good clinical results. Placental protein 12 ist not suited for selecting patients. Placental protein 14 shows typical changes after the application of polyvalent immunoglobulin and could be an important prognostic factor. Tumor necrosis factor alpha seems to be useful for selecting patients for immunotherapy, because in cases of habitual abortions this factor can be a sign for immunological causes. In the late phase of pregnancy, early pregnancy factor is also an indicator for disturbances of pregnancy.
Authors	T Römer, W Straube, M Meisel
Journal	Immunitat und Infektion (Immun Infekt) Vol. 22 Issue 2 Pg. 55-7 (Apr 1994) Germany
Vernacular Title	Passive Immuntherapie mit Venimmun zur Prävention von habituellen Aborten--Early Pregnancy Factor, Plazentaprotein 12, Plazenta-protein 14, Tumornekrosefaktor-alpha--Parameter zur Uberwachung der Immuntherapie.
PMID	7959861 (Publication Type: Clinical Trial, Journal Article)
Chemical References	Chaperonin 10 Glycodelin Glycoproteins IGFBP1 protein, human IgG, sulfonated Immunoglobulin G Insulin-Like Growth Factor Binding Protein 1 Insulin-Like Growth Factor Binding Proteins PAEP protein, human Peptides Pregnancy Proteins Suppressor Factors, Immunologic Tumor Necrosis Factor-alpha early pregnancy factor
Topics	Abortion, Habitual (blood, prevention & control) Chaperonin 10 Female Glycodelin Glycoproteins Humans Immunization, Passive Immunoglobulin G (therapeutic use) Insulin-Like Growth Factor Binding Protein 1 Insulin-Like Growth Factor Binding Proteins Peptides (blood) Pregnancy Pregnancy Proteins (blood) Suppressor Factors, Immunologic Tumor Necrosis Factor-alpha (metabolism)

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