Isolation of equine herpesvirus type 2 (equine gammaherpesvirus 2) from foals with keratoconjunctivitis.

Abstract

Ocular problems characterized by conjunctivitis, epiphora, and keratopathy were detected in 35 of 80 Thoroughbred weanling foals that also had respiratory disease. Ocular problems were determined to be caused by infection with equine herpesvirus type 2 (EHV-2) and were successfully treated with ophthalmic medication containing idoxuridine. Equine herpesvirus type 2 isolated from 3 of 5 foals from which samples were collected. The identity of the causative virus as EHV-2 was confirmed by use of electron microscopy, restriction endonuclease DNA fingerprinting, and Southern blot analysis.

• Authors: P N COllinson, J L O'Rielly, N Ficorilli, M J Studdert
• Journal: Journal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 205 Issue 2 Pg. 329-31 (Jul 15 1994) ISSN: 0003-1488 [Print] United States
• PMID: 7928614 (Publication Type: Journal Article)

Chemical References

• DNA, Viral

Topics

• Animals
• Blotting, Southern
• Cells, Cultured
• DNA Fingerprinting
• DNA, Viral (analysis)
• Herpesviridae (genetics, isolation & purification, ultrastructure)
• Herpesviridae Infections (veterinary, virology)
• Horse Diseases (virology)
• Horses
• Keratoconjunctivitis, Infectious (virology)
• Microscopy, Electron