Cutaneous mastocytosis complicating pregnancy.

Abstract

BACKGROUND:

Telangiectasia macularis eruptiva perstans, a rare form of cutaneous mastocytosis associated with elevated histamine excretion, has not previously been reported to complicate pregnancy.

CASE:

A woman presented in the late second trimester with an anaphylactoid reaction, rash, uterine contractions, and vaginal bleeding. Skin biopsy revealed perivascular mast-cell infiltration. Her urinary histamine excretion was markedly elevated. She was treated successfully with tocolytics and antihistamines.

CONCLUSION:

Elevated histamine excretion in biopsy-proven cutaneous mastocytosis may be associated with preterm labor.

• Authors: J G Donahue, J B Lupton, A M Golichowski
• Journal: Obstetrics and gynecology (Obstet Gynecol) Vol. 85 Issue 5 Pt 2 Pg. 813-5 (May 1995) ISSN: 0029-7844 [Print] United States
• PMID: 7724121 (Publication Type: Case Reports, Journal Article)

Chemical References

• Magnesium Sulfate

Topics

• Adult
• Apgar Score
• Biopsy
• Cesarean Section
• Female
• Humans
• Infant, Newborn
• Magnesium Sulfate (therapeutic use)
• Obstetric Labor, Premature (drug therapy)
• Pregnancy
• Pregnancy Complications (diagnosis, pathology)
• Pregnancy Trimester, Second
• Skin (pathology)
• Urticaria Pigmentosa (drug therapy, etiology, pathology)