[A trial of the use of the preparation Arthrotec for treating rheumatic diseases].

Abstract

A clinical trial of arthrotek (Searle) in 60 RA patients aged 16-77 years demonstrated its high anti-inflammatory activity in 47 of them. These patients have received a complete treatment course, 10 patients were not included in the overall estimations because of side affects (gastric pains and nausea) causing them to withdraw early in the treatment course, 3 patients were nonresponders. The responders experienced attenuation of joint pain, morning stiffness. Inflammation in some joints declined, the articular index decreased.

• Authors: V A Nasonova, Ia A Sigidin, Iu V Murav'ev, O I Lebedeva, V I Burtsev, Z P Rashchupkina, V P Krikunov, A V Kuzin, E L Nasonov, N V Chichasova
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 67 Issue 1 Pg. 34-8 ( 1995) ISSN: 0040-3660 [Print] Russia (Federation)
• Vernacular Title: Opyt primeneniia preparata atrotek dlia lecheniia revmaticheskikh zabolevaniĭ.
• PMID: 7709352 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Multicenter Study)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Arthrotec
• Drug Combinations
• Tablets
• Misoprostol
• Diclofenac

Topics

• Adolescent
• Adult
• Aged
• Anti-Inflammatory Agents, Non-Steroidal (adverse effects, therapeutic use)
• Diclofenac (adverse effects, therapeutic use)
• Drug Combinations
• Female
• Humans
• Male
• Middle Aged
• Misoprostol (adverse effects, therapeutic use)
• Remission Induction
• Rheumatic Diseases (diagnosis, drug therapy)
• Russia
• Tablets