[Neurologic manifestations following accidental exposure to pyralene and its thermal degradation products].

Abstract

After five young women were exposed to pyralene and its thermal degradation products all developed a rich functional syndrome which could be explained by the traumatic effect of the accident. Nevertheless, in 3 of the women, abnormal somesthetic evoked potentials were observed including 2 with neurological lesions detectable radiologically. Polychlorobiphenyl derivates are toxic for the peripheral nervous system as has been observed in several recent exposure situations. Inversely, any effect on the central nervous system is still under debate.

• Authors: J Reis, C Tranchant, J L Dietemann, J M Warter
• Journal: Revue neurologique (Rev Neurol (Paris)) Vol. 151 Issue 1 Pg. 47-51 (Jan 1995) ISSN: 0035-3787 [Print] France
• Vernacular Title: Manifestations neurologiques au décours d'une exposition accidentelle au pyralène et à ses produits de dégradation thermique.
• PMID: 7676129 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Neurotoxins
• pyralene
• Polychlorinated Biphenyls

Topics

• Accidents, Occupational
• Adult
• Brain (drug effects)
• Evoked Potentials (drug effects)
• Explosions
• Female
• France
• Hot Temperature
• Humans
• Magnetic Resonance Imaging
• Neurotoxins
• Occupational Exposure
• Polychlorinated Biphenyls (toxicity)